CAS 94-19-9

Sulfaethidole

Description:

Sulfaethidole is a sulfonamide antibiotic that belongs to the class of drugs known as sulfa drugs, which are characterized by their sulfonamide functional group. It is primarily used for its antibacterial properties, particularly against certain bacterial infections. The chemical structure of sulfaethidole includes a sulfonamide group attached to an ethyl group and a thiazole ring, which contributes to its pharmacological activity. This compound exhibits bacteriostatic effects by inhibiting the synthesis of folic acid in bacteria, thereby interfering with their growth and reproduction. Sulfaethidole is typically administered orally and is known for its relatively low toxicity compared to other antibiotics. However, like other sulfonamides, it may cause allergic reactions in some individuals and can lead to side effects such as gastrointestinal disturbances or skin rashes. Its use has declined with the advent of more effective antibiotics, but it remains a significant example of early antimicrobial therapy. As with any medication, it is essential to use sulfaethidole under medical supervision to ensure safety and efficacy.

Formula: C₁₀H₁₂N₄O₂S₂

InChI: InChI=1S/C10H12N4O2S2/c1-2-9-12-13-10(17-9)14-18(15,16)8-5-3-7(11)4-6-8/h3-6H,2,11H2,1H3,(H,13,14)

InChI key: InChIKey=SVYBEBLNQGDRHF-UHFFFAOYSA-N

SMILES: S(NC=1SC(CC)=NN1)(=O)(=O)C2=CC=C(N)C=C2

Synonyms:

• 2-(p-Aminobenzenesulfamido)-5-ethyl-1,3,4-thiadiazole
• 2-(p-Aminobenzenesulfonamido)-5-ethylthiadiazole
• 2-(p-Aminophenylsulfonamido)-5-ethyl-1,3,4-thiadiazole
• 2-Ethyl-5-sulfanilamido-1,3,4-thiadiazol
• 2-Sulfanilamido-5-ethyl-1,3,4-thiadiazole
• 2-Sulfanilamido-5-ethylthiadiazole
• 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide
• 5-Sulfanilamido-2-ethyl-1,3,4-thiadiazole
• Aethazol
• Benzenesulfonamide, 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-
• Berlophen
• Etazol
• Etazole
• Ethazole
• Ethazole (pharmaceutical)
• Globucid
• Globucin
• N1-(5-ethyl-1,3,4-thiadiazol-2-yl)sulphanilamide
• N¹-(5-Ethyl-1,3,4-thiadiazol-2-yl)sulfanilamide
• Sethadil
• Sul-Spansion
• Sul-Spantab
• Sulfa-Perlongit
• Sulfaethidiole
• Sulfaethidol
• Sulfaethylthiadiazole
• Sulfanilamide, N¹-(5-ethyl-1,3,4-thiadiazol-2-yl)-
• Sulphaethidole
• Vk 55

Sulfaethylthiadiazole

CAS: 94-19-9

Formula: C₁₀H₁₂N₄O₂S₂

Color and Shape: Neat

Molecular weight: 284.36

Ref: 04-C16990660

4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide

CAS: 94-19-9

4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonamide (ATBS) is an antimicrobial agent that inhibits the growth of bacteria by binding to metal hydroxides in their cell walls. This binding prevents the formation of an antibiotic-inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. ATBS has been shown to be effective against infectious diseases such as bowel disease and infectious diarrhea. ATBS also has hypoglycemic effects and can be used to treat diabetes mellitus type 2. It may also have a role in treating autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, or Crohn's disease. ATBS is not very soluble in water but is soluble in liquid paraffin and lipids. ATBS is metabolized by p-hyd

Formula: C₁₀H₁₂N₄O₂S₂

Purity: Min. 95%

Molecular weight: 284.36 g/mol

Ref: 3D-AAA09419