CAS 94-20-2

Chlorpropamide

Description:

Chlorpropamide is a sulfonylurea class medication primarily used in the management of type 2 diabetes mellitus. It functions as an oral hypoglycemic agent by stimulating insulin secretion from the pancreatic beta cells and enhancing the sensitivity of peripheral tissues to insulin. The chemical formula of chlorpropamide is C10H13ClN2O3S, and it features a chlorinated aromatic ring, a sulfonamide group, and an aliphatic side chain. This compound is typically administered in tablet form and is characterized by its relatively long half-life, which allows for once-daily dosing. Chlorpropamide is known to have potential side effects, including hypoglycemia, gastrointestinal disturbances, and allergic reactions. It is contraindicated in patients with certain conditions, such as severe renal impairment or sulfonamide allergies. Additionally, due to its long duration of action, careful monitoring of blood glucose levels is essential to avoid adverse effects. Overall, chlorpropamide remains a significant option in the pharmacological management of diabetes, particularly in patients who respond well to sulfonylureas.

Formula: C₁₀H₁₃ClN₂O₃S

InChI: InChI=1S/C10H13ClN2O3S/c1-2-7-12-10(14)13-17(15,16)9-5-3-8(11)4-6-9/h3-6H,2,7H2,1H3,(H2,12,13,14)

InChI key: InChIKey=RKWGIWYCVPQPMF-UHFFFAOYSA-N

SMILES: S(NC(NCCC)=O)(=O)(=O)C1=CC=C(Cl)C=C1

Synonyms:

• 1-(4-Chloro-benzenesulfonyl)-3-n-propyl-urea
• 1-(4-Chlorobenzenesulphonyl)-3-Propylurea
• 1-(4-Chlorophenyl)sulfonyl-3-propyl-urea
• 1-(4-Chlorophenyl)sulfonyl-3-propylurea
• 1-(4-Chlorophenylsulfonyl)-3-propylurea
• 1-(p-Chlorobenzenesulfonyl)-3-propylurea
• 1-(p-Chlorophenylsulfonyl)-3-propylurea
• 1-Propyl-3-(p-chlorobenzenesulfonyl)urea
• 4-Chloro-N-(propylcarbamoyl)benzenesulfonamide
• 4-Chloro-N-[(propylamino)carbonyl]benzenesulfonamide
• Adiaben
• Asucrol
• Benzenesulfonamide, 4-chloro-N-[(propylamino)carbonyl]-
• Benzenesulfonamide, N-[Propylaminocarbonyl]-4-Chloro-
• Catanil
• Chlorodiabina
• Chloronase
• Chloropropamide
• Chlorpropamid
• Chlorpropamide BP/ USP
• Clorpropamida
• Diabaril
• Diabechlor
• Diabenal
• Diabenese
• Diabeneza
• Diabet-Pages
• Diabetoral
• Diabinese
• Glisema
• Meldian
• Melitase
• Millinese
• N-(4-Chlorophenylsulfonyl)-N'-propylurea
• N-(p-Chlorobenzenesulfonyl)-N'-propylurea
• N-Propyl-N'-(p-chlorobenzenesulfonyl)urea
• N-Propyl-N'-p-chlorphenylsulfonylcarbamide
• Nsc 44634
• Nsc 626720
• P 607
• Pamidin
• Stabinol
• U 9818

1-(4-Chlorophenylsulfonyl)-3-propylurea

CAS: 94-20-2

Formula: C₁₀H₁₃ClN₂O₃S

Purity: >99.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 276.74

Ref: 3B-C1220

Chlorpropamide

CAS: 94-20-2

Increases insulin secretion

Formula: C₁₀H₁₃ClN₂O₃S

Color and Shape: White to beige, Powder or crystalline powder

Molecular weight: 276.74

Ref: 02-J64110

Chlorpropamide

CAS: 94-20-2

Color and Shape: Neat

Ref: 61-FOR1635.00

Chlorpropamide

CAS: 94-20-2

Sulfonamides used as drugs

Formula: C₁₀H₁₃ClN₂O₃S

Color and Shape: White Crystalline Powder

Molecular weight: 276.74

Ref: 45-1126009

1-[(4-chlorobenzene)sulfonyl]-3-propylurea

CAS: 94-20-2

Formula: C₁₀H₁₃ClN₂O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 276.7398

Ref: IN-DA003OUS

Chlorpropamide

CAS: 94-20-2

Chlorpropamide (Diabinese) is a sulfonylurea hypoglycemic agent used in the treatment of non-insulin-dependent diabetes mellitus not responding to dietary

Formula: C₁₀H₁₃ClN₂O₃S

Purity: 98.90%

Color and Shape: Crystals From Dil Ethanol Physical Description White Crystalline Powder With A Slight Odor (Ntp 1992)

Molecular weight: 276.74

Ref: TM-T0490

Chlorpropamide

CAS: 94-20-2

Formula: C₁₀H₁₃ClN₂O₃S

Purity: (Titration) 98.0 - 102.0 %

Color and Shape: White powder

Molecular weight: 276.74

Ref: 7W-GL6406

Chlorpropamide

CAS: 94-20-2

Chlorpropamide

Purity: 99%

Molecular weight: 276.74g/mol

Ref: 54-OR1029919

Chlorpropamide

CAS: 94-20-2

Chlorpropamide

Purity: ≥98%

Molecular weight: 276.74g/mol

Ref: 54-BUP19619

Chlorpropamide

Controlled Product

CAS: 94-20-2

Formula: C₁₀H₁₃ClN₂O₃S

Color and Shape: Neat

Molecular weight: 276.74

Ref: 04-C11577000

Chlorpropamide

Controlled Product

CAS: 94-20-2

Formula: C₁₀H₁₃ClN₂O₃S

Color and Shape: Neat

Molecular weight: 276.74

Ref: 86-MM1635.00

Chlorpropamide

CAS: 94-20-2

Formula: C₁₀H₁₃ClN₂O₃S

Molecular weight: 276.74

Ref: 4Z-C-496001

Chlorpropamide

Controlled Product

CAS: 94-20-2

Applications Chlorpropamide is a sulfonylurea derivative. Chlorpropamide is a long acting hyopglycemic agent. Chlorpropamide is used in the treatment of diabetes metilus type 2. Chlorpropamide acts to increase the secretion of insulin and is not effective in patients who do not have pancreatic beta cell function.
References Turner, R.C. et al.: Diabetes, 27, 241 (1978); Grinnell, E.H. et al.: Am. J. Med. Sci., 253, 312 (1967); Taylor, J.A.: Clin. Pharmacol. Therap., 13, 710 (1972);

Formula: C₁₀H₁₃ClN₂O₃S

Color and Shape: White To Light Yellow

Molecular weight: 276.74

Ref: TR-C424800

4-Chloro-N-(propylcarbamoyl)benzenesulfonamide

CAS: 94-20-2

Formula: C₁₀H₁₃ClN₂O₃S

Purity: 99%

Color and Shape: Solid

Molecular weight: 276.74

Ref: 10-F242203

Chlorpropamide

CAS: 94-20-2

Hypoglycemic agent

Formula: C₁₀H₁₃ClN₂O₃S

Purity: Min. 95%

Color and Shape: White Off-White Powder

Molecular weight: 276.74 g/mol

Ref: 3D-FC20409