CAS 94-53-1

1,3-Benzodioxole-5-carboxylic acid

Description:

1,3-Benzodioxole-5-carboxylic acid, with the CAS number 94-53-1, is an organic compound characterized by its bicyclic structure, which includes a benzodioxole moiety and a carboxylic acid functional group. This compound typically appears as a white to off-white crystalline solid and is soluble in polar organic solvents. It exhibits acidic properties due to the presence of the carboxylic acid group, which can donate protons in solution. The compound is known for its potential applications in pharmaceuticals and organic synthesis, often serving as an intermediate in the production of various bioactive molecules. Additionally, its structure allows for various chemical modifications, making it a versatile building block in organic chemistry. The compound's stability and reactivity can be influenced by the substituents on the benzodioxole ring, which can affect its physical and chemical properties. Safety data indicates that, like many organic acids, it should be handled with care to avoid irritation or adverse reactions.

Formula: C₈H₆O₄

InChI: InChI=1S/C8H6O4/c9-8(10)5-1-2-6-7(3-5)12-4-11-6/h1-3H,4H2,(H,9,10)

InChI key: InChIKey=VDVJGIYXDVPQLP-UHFFFAOYSA-N

SMILES: C(O)(=O)C=1C=C2C(=CC1)OCO2

Synonyms:

• 1,3-Benzodioxole-5-Carboxylic Acid
• 1,3-Dioxaindane-5-carboxylic acid
• 1-3-Benzodioxole-5-carboxylic acid~3,4-(Methylenedioxy)benzoic acid
• 2H-1,3-Benzodioxole-5-carboxylic acid
• 3,4-Dioxymethylenebenzoic acid
• 3,4-Methylendioxy-benzoic acid
• 3,4-Methylenedioxybenzenecarboxylic acid
• 3,4-Methylenedioxybenzoic acid
• 5-Benzodioxolecarboxylic acid
• Benzo[d][1,3]dioxole-5-carboxylic acid
• Heliotropic acid
• NSC 10072
• NSC 119055
• Piperonylic acid, (3,4-Methylenedioxybenzoic acid)
• Protocatechuic acid methylene ether

Piperonylic Acid

CAS: 94-53-1

Formula: C₈H₆O₄

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 166.13

Ref: 3B-P0459

Piperonylic acid, 98+%

CAS: 94-53-1

Piperonylic acid is used as pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has no

Formula: C₈H₆O₄

Purity: 98+%

Color and Shape: Crystals or powder or crystalline powder, White to yellow or cream to pale brown

Molecular weight: 166.13

Ref: 02-A14105

Benzo[d][1,3]dioxole-5-carboxylic acid

CAS: 94-53-1

Formula: C₈H₆O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 166.1308

Ref: IN-DA003TT3

Piperonylic acid

CAS: 94-53-1

Formula: C₈H₆O₄

Molecular weight: 166.13

Ref: 7W-GK7158

Piperonylic acid

CAS: 94-53-1

Piperonylic acid

Purity: ≥98%

Molecular weight: 166.13g/mol

Ref: 54-BUP18943

1,3-Benzodioxole-5-carboxylic acid

CAS: 94-53-1

1,3-Benzodioxole-5-carboxylic acid

Purity: 98%

Color and Shape: White Powder

Molecular weight: 166.13084g/mol

Ref: 54-OR4989

Piperonylic acid

CAS: 94-53-1

Piperonylic acid (2H-1,3-benzodioxole-5-carboxylic acid) is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-

Formula: C₈H₆O₄

Purity: 99.93%

Color and Shape: Solid

Molecular weight: 166.13

Ref: TM-TN6848

Piperonylic Acid

Controlled Product

CAS: 94-53-1

Applications Piperonylic Acid is a compound closely mimicking the structure of transcinnamic acid involved in the phenylpropanoid pathway in plant physiology.
References Schalk, M. et al.: Plant Physiol., 118, 209 (1998);

Formula: C₈H₆O₄

Color and Shape: Neat

Molecular weight: 166.13

Ref: TR-P490450

1,3-Benzodioxole-5-carboxylic acid

CAS: 94-53-1

1,3-Benzodioxole-5-carboxylic acid (1,3BDC) is a benzoxazinoid that was identified as an inhibitor of malonic acid carboxylase. 1,3BDC is not active against bacteria and fungi in vitro. It has been shown to be effective in preventing and treating insect resistance by interfering with the synthesis of chitin. The compound binds to the active site of the enzyme and inhibits its activity by blocking the entrance of acetic acid into the active site. 1,3BDC also has a protective effect on balloon injury in rats by reducing inflammation and apoptosis in skin cells. The mechanism of action for this effect is not known but may involve hydrogen bonding interactions with proteins or 3,4-methylenedioxycinnamic acid-induced transcriptional activation.

Formula: C₈H₆O₄

Purity: Min. 98.0%

Color and Shape: Powder

Molecular weight: 166.13 g/mol

Ref: 3D-FB34327

3,4-(Methylenedioxy)benzoic acid

CAS: 94-53-1

Formula: C₈H₆O₄

Purity: 98%

Color and Shape: Solid, Beige powder

Molecular weight: 166.132

Ref: 10-F022643