CAS 94034-78-3

somatotropin-releasing hormone (1-32)amide, His(1),Nle(27)-

Description:

Somatotropin-releasing hormone (1-32) amide, specifically with the modifications His(1) and Nle(27), is a peptide hormone that plays a crucial role in stimulating the release of growth hormone from the anterior pituitary gland. This substance is a derivative of the natural somatotropin-releasing hormone (SRH), which consists of a chain of 32 amino acids. The modifications at positions 1 and 27 enhance its biological activity and stability. Characteristically, this peptide exhibits a high affinity for growth hormone-releasing hormone receptors, facilitating the physiological processes associated with growth and metabolism. It is typically administered in research settings to study growth hormone dynamics and related metabolic pathways. The amide form indicates that the C-terminus of the peptide is amidated, which is a common modification that can enhance the peptide's stability and bioactivity. Overall, somatotropin-releasing hormone (1-32) amide, His(1),Nle(27)- is significant in endocrinology and biochemistry for its role in growth regulation and potential therapeutic applications.

Formula: C₁₅₉H₂₆₅N₅₁O₄₆

Synonyms:

• somatotropin-releasing hormone (1-32)amide, His(1),Nle(27)-
• Somatoliberin(human pancreatic islet), 1-L-histidine-27-L-norleucine-32-glycinamide-33-de-L-glutamicacid-34-de-L-serine-35-de-L-asparagine-36-de-L-glutamine-37-de-L-glutamicacid-38-de-L-arginine-39-deglycine-40-de-L-alanine-41-de-L-arginine-42-de-L-alanine-43-de-L-arginine-44-de-L-leucinamide-

[His1,Nle27] GHRF (1-32), amide, human

CAS: 94034-78-3

[His1,Nle27] GHRF (1-32), amide, human is a potent GHRH analog with high GHRHR affinity.

Formula: C₁₅₉H₂₆₅N₅₁O₄₆

Color and Shape: Solid

Molecular weight: 3627.12

Ref: TM-T76317