CAS 940867-25-4

Docetaxel-d9

CAS: 940867-25-4

Formula: C₄₃H₄₄D₉NO₁₄

Color and Shape: Off-White Solid

Molecular weight: 816.94

Ref: 4Z-D-192

Docetaxel-d9

Controlled Product

CAS: 940867-25-4

Applications A labelled semisynthetic derivative of Paclitaxel. An antimitotic agent that promotes the assembly of micro-tubules and inhibits their de-polymerization to free tubulin. An antineoplastic.
References Ringel, I., et al.: J. Natl. Cancer Inst., 83, 288 (1991), Extra, J.-M., et al.: Cancer Res., 53, 1037 (1993)

Formula: C₄₃D₉H₄₄NO₁₄

Color and Shape: Neat

Molecular weight: 816.93

Ref: TR-D494422

Docetaxel-d9

CAS: 940867-25-4

Docetaxel-d9 is a deuterated compound of Docetaxel. Docetaxel has a CAS number of 114977-28-5. Docetaxel is a microtubule inhibitor that inhibits microtubule disassembly (IC50: 0.2 μM).

Formula: C₄₃H₄₄D₉NO₁₄

Color and Shape: Solid

Molecular weight: 816.93

Ref: TM-TMIJ-0221

Docetaxel-d9

CAS: 940867-25-4

Docetaxel is a chemotherapy agent that is used to treat a number of cancers, including breast cancer, prostate cancer, lung cancer, and bladder cancer. Docetaxel-d9 is a solubilized form of docetaxel that has been validated for use in the treatment of cancer. It has been shown to inhibit the growth kinetics of carcinoma cell lines in vitro. The uptake of docetaxel-d9 was studied on bladder and plasma samples. In addition, it was found that docetaxel-d9 can be detected by a Western blot assay (WST-1). Docetaxel-d9 is also soluble in water and organic solvents such as acetone or ethanol.

Formula: C₄₃H₅₃NO₁₄

Purity: Min. 95%

Molecular weight: 816.9 g/mol

Ref: 3D-QMB86725