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CAS 94088-85-4

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Doxycycline calcium

Description:
Doxycycline calcium is a semisynthetic tetracycline antibiotic that is derived from oxytetracycline. It is primarily used to treat a variety of bacterial infections, including respiratory tract infections, urinary tract infections, and certain sexually transmitted infections. The compound exhibits broad-spectrum antimicrobial activity by inhibiting protein synthesis in bacteria, which makes it effective against both Gram-positive and Gram-negative organisms. Doxycycline calcium is characterized by its stability in the presence of light and heat, which enhances its shelf life compared to other tetracyclines. It is typically administered orally and has good bioavailability, allowing for effective absorption in the gastrointestinal tract. The calcium salt form improves its solubility and stability. Common side effects may include gastrointestinal disturbances, photosensitivity, and potential effects on bone and teeth development in children. As with all antibiotics, it is important to use doxycycline calcium judiciously to prevent the development of antibiotic resistance.
Formula:C22H24N2O8·2Ca
InChI:InChI=1S/C22H24N2O8.2Ca/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;;/h4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);;/t7-,10+,14+,15-,17-,22-;;/m0../s1
InChI key:InChIKey=CEGLWWYOEXTDIB-QFWOMMJSSA-N
SMILES:O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)([C@@H](O)[C@]3(C(=C2O)C(=O)C=4C([C@@H]3C)=CC=CC4O)[H])[H].[Ca]
Synonyms:
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, calcium salt (1:2), (4S,4aR,5S,5aR,6R,12aS)-
  • 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, calcium salt, (4S,4aR,5S,5aR,6R,12aS)-, hydrate (1:1:1)
  • Doxycycline Calcium
  • dicalcium (5R,5aR,6S,6aR,7S,9Z,10aS)-9-[amino(hydroxy)methylidene]-7-(dimethylamino)-5-methyl-8,10,11-trioxo-5,6,6a,7,8,9,10,11-octahydrotetracene-1,6,10a,12(5aH)-tetrolate
  • dicalcium (5R,5aR,6S,6aR,7S,9Z,10aS)-9-[amino(oxido)methylidene]-7-(dimethylamino)-10a-hydroxy-5-methyl-8,10,11-trioxo-5,5a,6,6a,7,8,9,10,10a,11-decahydrotetracene-1,6,12-triolate
  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, calcium salt (1:2), [4S-(4α,4aα,5α,5aα,6α,12aα)]-
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