CAS 940943-37-3

Ethanethioic acid, S-[2-[6-[[[4-[3-(dimethylamino)propoxy]phenyl]sulfonyl]amino]-3-pyridinyl]-2-oxoethyl] ester

CAS: 940943-37-3

Formula: C₂₀H₂₅N₃O₅S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 451.5596

Ref: IN-DA00352M

KD 5170

CAS: 940943-37-3

KD 5170 is a potent and selective inhibitor of histone H3K9 methyltransferases. It has been shown to inhibit the growth of tumor xenografts in mice. KD 5170 also inhibits the acetylation of histone H4K5, which is necessary for the activation of transcription factors that control cell differentiation and proliferation. This drug also induces necrotic cell death by inhibiting mitochondrial membrane potential and oxidative DNA damage. KD 5170 may be clinically effective against cancer, as it has been shown to have an inhibitory effect on tumor xenografts in mice.
This drug has natural compounds that are being studied for their effects on cancer cells, specifically those with mutations in genes related to TNF-related apoptosis-inducing ligand (TNFAIP6) or programmed cell death 1 (PDCD1).

Formula: C₂₀H₂₅N₃O₅S₂

Purity: Min. 95%

Molecular weight: 451.56 g/mol

Ref: 3D-QMB94337

KD 5170

CAS: 940943-37-3

KD 5170, a pan inhibitor of histone deacetylases (HDACs), demonstrates widespread antitumor activity both in vitro and in vivo [1].

Formula: C₂₀H₂₅N₃O₅S₂

Color and Shape: Solid

Molecular weight: 451.56

Ref: TM-T21628