CAS 941294-31-1

4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine

Description:

4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine is a heterocyclic organic compound characterized by its pyrimidine core, which is a six-membered ring containing two nitrogen atoms at positions 1 and 3. The presence of a chlorine atom at the 4-position and a 2-methyl-1H-imidazol-1-yl group at the 6-position contributes to its unique chemical properties. This compound is typically a solid at room temperature and is soluble in polar organic solvents. It exhibits biological activity, making it of interest in medicinal chemistry, particularly in the development of pharmaceuticals. The imidazole moiety can participate in hydrogen bonding and coordination with metal ions, enhancing its reactivity. Additionally, the chlorine substituent can influence the compound's electronic properties and reactivity, potentially affecting its interactions with biological targets. Overall, 4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine is a versatile compound with applications in drug discovery and development.

Formula: C₈H₇ClN₄

InChI: InChI=1S/C8H7ClN4/c1-6-10-2-3-13(6)8-4-7(9)11-5-12-8/h2-5H,1H3

InChI key: InChIKey=KTZYOMJEOTYZAX-UHFFFAOYSA-N

SMILES: CC=1N(C=2C=C(Cl)N=CN2)C=CN1

Synonyms:

• 4-chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine
• Pyrimidine, 4-chloro-6-(2-methyl-1H-imidazol-1-yl)-
• 4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine98%
• 6-(2-Methylimidazol-1-yl)-4-chloropyrimidine
• 4-chloro-6-(2-methylimidazol-1-yl)pyrimidine
• 4-chloro-6-(2-Methyl-1H-iMidazol-1-yl)pyriMide
• 4-chloro-6-(2-methyl-1-imidazolyl)pyrimidine
• 1-(6-Chloropyrimidin-4-yl)-2-methyl-1H-imidazole

4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine

CAS: 941294-31-1

Formula: C₅₆H₈₄O₂₁S₂

Color and Shape: Solid

Molecular weight: 1157.3836

Ref: IN-DA003L5M

4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine

CAS: 941294-31-1

4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine

Formula: C₈H₇ClN₄

Purity: 98%

Color and Shape: light yellow solid

Molecular weight: 194.62g/mol

Ref: 54-OR11462

4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine

Controlled Product

CAS: 941294-31-1

Applications 4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine is a reagent used in the synthesis of [(aminosulfonylaminoalkyl)piperidinyl]pyrimidines and -quinazolines as PC-1 inhibitors for alleviating hERG interactions through structure based design.
References Patel, S. D., et al.: Bioorg. Med. Chem. Lett., 19, 3339 (2009); Patel, S. D., et al.: Bioorg. Med. Chem. Lett., 20, 2685 (2010)

Formula: C₅₆H₈₄O₂₁S₂

Color and Shape: Neat

Molecular weight: 1157.384

Ref: TR-C587548

4-Chloro-6-(2-methyl-1H-imidazol-1-yl)pyrimidine

CAS: 941294-31-1

Versatile small molecule scaffold

Formula: C₈H₇ClN₄

Purity: Min. 95%

Molecular weight: 194.62 g/mol

Ref: 3D-RMB29431