CAS 942-27-8

1H-Indole-3-ethanamine, N-methyl-, hydrochloride (1:1)

Description:

1H-Indole-3-ethanamine, N-methyl-, hydrochloride (1:1), commonly referred to as N-methyltryptamine, is a chemical compound characterized by its indole structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. This substance is a derivative of tryptamine, featuring a methyl group attached to the nitrogen atom of the ethylamine side chain. As a hydrochloride salt, it is typically encountered in a crystalline form, which enhances its solubility in water and facilitates its handling in laboratory settings. The compound is known for its potential psychoactive properties and has been studied for its effects on serotonin receptors. Its molecular formula reflects the presence of carbon, hydrogen, nitrogen, and chlorine atoms, contributing to its unique chemical behavior. In terms of safety, like many amines, it may pose risks if ingested or improperly handled, necessitating appropriate safety measures during use. Overall, N-methyltryptamine is of interest in both pharmacological research and the study of psychoactive substances.

Formula: C₁₁H₁₄N₂·ClH

InChI: InChI=1S/C11H14N2.ClH/c1-12-7-6-9-8-13-11-5-3-2-4-10(9)11;/h2-5,8,12-13H,6-7H2,1H3;1H

InChI key: InChIKey=IVKQLFYZTJODMJ-UHFFFAOYSA-N

SMILES: C(CNC)C=1C=2C(NC1)=CC=CC2.Cl

Synonyms:

• 1H-Indole-3-ethanamine, N-methyl-, hydrochloride (1:1)
• 1H-Indole-3-ethanamine, N-methyl-, monohydrochloride
• 2-(1H-indol-3-yl)-N-methylethanaminium chloride
• 3-(2-(Methylamino)ethyl)indole monohydrochloride
• Indole, 3-(2-(methylamino)ethyl)-, monohydrochloride
• Indole, 3-[2-(methylamino)ethyl]-, hydrochloride
• N-Methyltryptamine hydrochloride

N-Methyltryptamine Hydrochloride

Controlled Product

CAS: 942-27-8

Applications N-Methyltryptamine is a N-monomethylated derivative of tryptamine. N-Methyltryptamine, unlike its unmethylated counterpart, does not produce any psychoactive effects. High levels of N-Methyltryptamine have been found in cisternal cerebrospinal fluid of patients with acute paranoid schizophrenia.
References Schmid, C. et al.: J. Neurosci., 30, 13513 (2010); Uebelhack, R. et al.: Biomed. Biochim. Acta, 42, 1343 (1983);

Formula: C₁₁H₁₅ClN₂

Color and Shape: Neat

Molecular weight: 210.7

Ref: TR-M331920

N-Methyltryptamine hydrochloride

Controlled Product

CAS: 942-27-8

N-Methyltryptamine hydrochloride is a chemical that has been shown to be an antagonist of the serotonin receptor 5-HT7 in vivo. This drug is also a potent inhibitor of acetylcholinesterase, which may be due to its ability to inhibit the methylation of serotonergic receptors. It has been shown to have clinical efficacy in treating depression, although it is not currently approved by the FDA for this use. N-Methyltryptamine hydrochloride has been shown to have an antidepressant effect in wild-type mice and in mouse models of depression. It inhibits the growth of cancer cells by inducing apoptosis and inhibiting cell proliferation.

Formula: C₁₁H₁₅ClN₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 210.7 g/mol

Ref: 3D-FM25972