CAS 942289-87-4

8-(4-aminophenyl)-2-morpholino-chromen-4-one

Description:

8-(4-Aminophenyl)-2-morpholino-chromen-4-one, identified by its CAS number 942289-87-4, is a synthetic organic compound that belongs to the class of chromenones, which are characterized by a chromene backbone. This compound features a morpholine ring and an amino group attached to a phenyl group, contributing to its potential biological activity. It typically exhibits properties such as moderate solubility in organic solvents and limited solubility in water, which is common for many organic compounds with complex structures. The presence of the amino and morpholino groups may impart specific reactivity and interaction capabilities, making it of interest in medicinal chemistry and drug development. Its structural features suggest potential applications in areas such as anti-inflammatory, antimicrobial, or anticancer research, although specific biological activities would need to be confirmed through empirical studies. Overall, this compound represents a unique scaffold for further exploration in pharmaceutical applications.

Formula: C₁₉H₁₈N₂O₃

InChI: InChI=1/C19H18N2O3/c20-14-6-4-13(5-7-14)15-2-1-3-16-17(22)12-18(24-19(15)16)21-8-10-23-11-9-21/h1-7,12H,8-11,20H2

SMILES: c1cc(c2ccc(cc2)N)c2c(c1)c(=O)cc(N1CCOCC1)o2

Synonyms:

• 4H-1-Benzopyran-4-one, 8-(4-aminophenyl)-2-(4-morpholinyl)-
• 8-(4-Aminophenyl)-2-(morpholin-4-yl)-4H-chromen-4-one

PI-828

CAS: 942289-87-4

PI-828

Purity: ≥98%

Molecular weight: 322.36g/mol

Ref: 54-BUP09226

PI 828

CAS: 942289-87-4

PI 828 is a drug that is used to treat both inflammatory bowel disease and cancer. It has an anti-inflammatory effect, which may be due to its ability to inhibit the production of pro-inflammatory cytokines in vitro. PI 828 also has an antiproliferative effect on human carcinoma cell lines, including inhibition of DNA polymerase activity, which may be due to its ability to bind to the cation channel of these cells. This drug has been shown to have synergistic effects with platinum-based chemotherapy drugs and is currently being studied for use in chemotherapeutic treatment.

Formula: C₁₉H₁₈N₂O₃

Purity: Min. 95%

Molecular weight: 322.36 g/mol

Ref: 3D-SMB28987

PI-828

CAS: 942289-87-4

PI-828 (LY 294002), a PI3K inhibitor, researches PI3K function and aids stem cell differentiation into mesoderm.

Formula: C₁₉H₁₈N₂O₃

Purity: 99.95%

Color and Shape: Solid

Molecular weight: 322.36

Ref: TM-T16528