CAS 943746-57-4

Cdk4 inhibitor V

CAS: 943746-57-4

Palbociclib is a CDK4 inhibitor that is used to treat cancer. It inhibits the activity of Cdk4 and prevents cells from progressing through the cell cycle, leading to their death. Palbociclib has been shown to inhibit tumor growth in humans with breast cancer and other proliferative disorders. The drug binds directly to Cdk4, preventing it from phosphorylating its substrates. This inhibition leads to the accumulation of p27, which suppresses the activity of cyclin-dependent kinases (CDKs). Inhibition of CDKs prevents cells from entering mitosis and results in cell death by apoptosis.

Formula: C₁₉H₁₈IN₃O₄

Purity: Min. 95%

Molecular weight: 479.27 g/mol

Ref: 3D-TMB74657