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CAS 943918-05-6

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4-Hydroxy-2-(trifluoromethyl)phenylboronic acid

Description:
4-Hydroxy-2-(trifluoromethyl)phenylboronic acid is an organoboron compound characterized by the presence of a boronic acid functional group, which is known for its ability to form reversible covalent bonds with diols, making it useful in various applications, including organic synthesis and medicinal chemistry. This compound features a trifluoromethyl group, which enhances its electronic properties and can influence its reactivity and solubility. The hydroxyl group contributes to its acidity and potential for hydrogen bonding. Typically, boronic acids like this one are utilized in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds. The trifluoromethyl substituent can also impart unique characteristics, such as increased lipophilicity and altered biological activity. Overall, 4-Hydroxy-2-(trifluoromethyl)phenylboronic acid is a versatile compound with significant implications in synthetic organic chemistry and pharmaceutical development. Its specific properties, such as melting point, solubility, and reactivity, would depend on the conditions under which it is used.
Formula:C7H6O3BF3
Synonyms:
  • 4-Hydroxy-2-(trifluoromethyl) phenyl boronic acid
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