CAS 944-73-0

1,3-Dimethyluric acid

Description:

1,3-Dimethyluric acid is a purine derivative and a methylated form of uric acid, characterized by the presence of two methyl groups attached to the nitrogen atoms at positions 1 and 3 of the uric acid structure. Its molecular formula is C7H8N4O3, and it has a molecular weight that reflects its composition of carbon, hydrogen, nitrogen, and oxygen. This compound is typically a white to off-white crystalline solid, exhibiting solubility in polar solvents such as water and alcohols, which is common for many uric acid derivatives. 1,3-Dimethyluric acid is of interest in biochemical research, particularly in studies related to purine metabolism and its potential implications in various physiological processes. Its structural modifications can influence its biological activity and interactions with enzymes involved in nucleic acid metabolism. As with many nitrogen-containing compounds, it may exhibit weak acidic properties, contributing to its behavior in biological systems. Safety data should be consulted for handling and exposure guidelines, as with any chemical substance.

Formula: C₇H₈N₄O₃

InChI: InChI=1S/C7H8N4O3/c1-10-4-3(8-6(13)9-4)5(12)11(2)7(10)14/h1-2H3,(H2,8,9,13)

InChI key: InChIKey=OTSBKHHWSQYEHK-UHFFFAOYSA-N

SMILES: O=C1C2=C(N(C)C(=O)N1C)NC(=O)N2

Synonyms:

• 1,3-Dimethyl-2,6,8-Trioxopurine
• 1,3-Dimethyl-7,9-dihydro-3H-purine-2,6,8-trione
• 1,3-Dimethyl-7,9-dihydropurine-2,6,8-trione
• 1,3-Dimethyluric acid
• 1,3-dimethyl-7,9-dihydro-1H-purine-2,6,8(3H)-trione
• 1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-1,3-dimethyl-
• Ba 2751
• Brn 0193698
• Nsc 95854
• Oxytheophylline
• Uric acid, 1,3-dimethyl-
• Uric acid, 1,3-dimethyl- (VAN)
• 7,9-Dihydro-1,3-dimethyl-1H-purine-2,6,8(3H)-trione
• 7,9-Dihydro-1,3-dimethyl-1H-purine-2,6,8(3H)-trione

1,3-Dimethyluric acid

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 196.1634

Ref: IN-DA0039GL

1,3-Dimethyluric acid

CAS: 944-73-0

1,3-Dimethyluric acid

Purity: ≥98%

Molecular weight: 196.16g/mol

Ref: 54-BUP14718

1,3-Dimethyluric acid

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Purity: ≥ 98%

Color and Shape: White, off-white or light-yellow powder

Molecular weight: 196.16

Ref: 7W-GL2263

Theophylline EP Impurity E

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Color and Shape: White To Off-White Solid

Molecular weight: 196.17

Ref: 4Z-T-608

1,3-Dimethyl-1H-Purine-2,6,8(3H,7H,9H)-Trione

CAS: 944-73-0

1,3-Dimethyl-1H-Purine-2,6,8(3H,7H,9H)-Trione

Purity: 98%

Molecular weight: 196.16g/mol

Ref: 54-OR1009200

1,3-Dimethyluric Acid

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 196.17

Ref: 3B-D6169

1,3-Dimethyluric acid

CAS: 944-73-0

1,3-Dimethyluric acid is a product of theophylline metabolism in man. It is one of the purine components in urinary calculi.

Formula: C₇H₈N₄O₃

Purity: 99.84% - 99.94%

Color and Shape: Solid

Molecular weight: 196.16

Ref: TM-T8075

1,3-Dimethyluric Acid

Controlled Product

CAS: 944-73-0

Applications 1,3-Dimethyluric Acid, is a metabolite of Caffeine (C080100), that is shown to have some of Its similar effects.
References Kalow, W., et al.: Clin. Pharmacol. Ther., 53, 503 (1993), Sharma, S., et al.: Cancer Res., 54, 5848 (1994), Sugawara, M., et al.: J. Biol. Chem., 275, 16473 (2000), Takeda, M., et al.: J. Pharmacol. Exp. Ther., 302, 666 (2002),

Formula: C₇H₈N₄O₃

Color and Shape: Neat

Molecular weight: 196.16

Ref: TR-D479735

Theophylline EP Impurity E

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Molecular weight: 196.17

Ref: ST-EA-CP-T59005

1,3-Dimethyl-1H-purine-2,6,8(3H,7H,9H)-trione

CAS: 944-73-0

Formula: C₇H₈N₄O₃

Purity: 97%

Molecular weight: 196.166

Ref: 10-F517648

1,3-Dimethyluric acid

Controlled Product

CAS: 944-73-0

1,3-Dimethyluric acid is a metabolite of caffeine. It is formed by the oxidative deamination of 1,3-dimethylxanthine in the liver. The concentrations of 1,3-dimethyluric acid are elevated in patients with chronic renal failure and those who are taking theophylline. The concentration–time curve for 1,3-dimethyluric acid was found to be linear and predictable after intravenous administration of caffeine at a dose of 10 mg/kg body weight in rats. This suggests that it is possible to estimate the rate of elimination from plasma after intravenous dosing with caffeine based on measurements of plasma concentrations and time. The metabolism of caffeine involves two pathways: oxidative deamination (1,3-dimethyluric acid) and demethylation (paraxanthine). It has been shown that the metabolites 1,3-dimethyluric acid and paraxanthine are formed by different metabolic pathways. The

Formula: C₇H₈N₄O₃

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 196.16 g/mol

Ref: 3D-FD08003