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CAS 94424-50-7

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Quinagolide hydrochloride

Description:
Quinagolide hydrochloride is a synthetic compound primarily used as a dopamine agonist, particularly in the treatment of conditions related to hyperprolactinemia, such as prolactin-secreting pituitary tumors. It acts by selectively stimulating dopamine D2 receptors, which helps to inhibit prolactin secretion from the pituitary gland. The substance is typically presented as a white to off-white crystalline powder and is soluble in water and organic solvents, making it suitable for various pharmaceutical formulations. Its molecular structure includes a quinoline ring, contributing to its pharmacological properties. Quinagolide hydrochloride is administered orally, and its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are essential for its therapeutic efficacy. As with any medication, it may have side effects, and its use should be monitored by healthcare professionals. Overall, Quinagolide hydrochloride represents an important therapeutic option in managing disorders associated with elevated prolactin levels.
Formula:C20H34ClN3O3S
InChI:InChI=1/C20H33N3O3S.ClH/c1-4-10-22-14-17(21-27(25,26)23(5-2)6-3)11-16-12-18-15(13-19(16)22)8-7-9-20(18)24;/h7-9,16-17,19,21,24H,4-6,10-14H2,1-3H3;1H/t16-,17+,19-;/m1./s1
Synonyms:
  • (3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloride
  • N,N-diethyl-N'-[(3S,4aS,10aR)-6-hydroxy-1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinolin-3-yl]sulfamide hydrochloride
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