CAS 944401-77-8

2-Amino-4-fluoropyridine

Description:

2-Amino-4-fluoropyridine is an organic compound characterized by its pyridine ring, which is a six-membered aromatic heterocycle containing one nitrogen atom. The presence of an amino group (-NH2) at the second position and a fluorine atom at the fourth position of the pyridine ring defines its structure and reactivity. This compound typically appears as a colorless to light yellow liquid or solid, depending on its form and purity. It is known for its potential applications in pharmaceuticals and agrochemicals, often serving as an intermediate in the synthesis of various biologically active compounds. The amino group contributes to its basicity, while the fluorine atom can enhance lipophilicity and influence the compound's interaction with biological targets. 2-Amino-4-fluoropyridine is soluble in polar solvents, and its reactivity can be attributed to the presence of both the amino and fluorine functional groups, making it a versatile building block in organic synthesis. Safety data should be consulted for handling and storage, as with any chemical substance.

Formula: C₅H₅FN₂

InChI: InChI=1/C5H5FN2/c6-4-1-2-8-5(7)3-4/h1-3H,(H2,7,8)

SMILES: c1c[nH]c(=N)cc1F

Synonyms:

• 2-Amino-4-Fluoro-pyridine
• 2-Pyridinamine, 4-Fluoro-
• 4-Fluor-2-pyridinamin
• 4-Fluoro-2-pyridinamine
• 4-Fluoropyridin-2-amine

2-Amino-4-fluoropyridine, 98%

CAS: 944401-77-8

It is an important raw material and intermediate used in organic synthesis agrochemical, pharmaceutical and dyestuff field. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand.

Formula: C₅H₅FN₂

Purity: 98%

Color and Shape: Solid, White to pale yellow to cream

Molecular weight: 112.11

Ref: 02-H64233

2-Amino-4-fluoropyridine

CAS: 944401-77-8

Formula: C₅H₅FN₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 112.1050

Ref: IN-DA003GFB

2-Amino-4-fluoropyridine

CAS: 944401-77-8

Formula: C₅H₅FN₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 112.11

Ref: 3B-A2976

2-Amino-4-fluoropyridine

CAS: 944401-77-8

2-Amino-4-fluoropyridine

Formula: C₅H₅FN₂

Purity: 97%

Color and Shape: yellow solid

Molecular weight: 112.105g/mol

Ref: 54-PC8826

2-Amino-4-fluoropyridine

CAS: 944401-77-8

Formula: C₅H₅FN₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 112.107

Ref: 10-F064880

2-Amino-4-fluoropyridine

CAS: 944401-77-8

2-Amino-4-fluoropyridine is an acylation reaction product of 2-amino-4-chloropyridine and a fatty acid. The diaminopyridine moiety is responsible for the inhibition of copper enzymes. In addition, fluorine substitution provides a higher operational stability. The synthesis of this compound is accomplished through the use of thionyl chloride in an operational procedure that includes heating at 180 °C for 4 hours. 2-Amino-4-fluoropyridine has been shown to be effective against some bacteria such as Mycobacterium tuberculosis and Legionella pneumophila, which are resistant to other agents. This drug also has antiplasmodial properties and can be used to treat malaria. The structure based design of this molecule was optimized by replacing chlorine with fluorine as well as introducing a n oxide group to provide a sterically more favorable conformation.

Formula: C₅H₅FN₂

Purity: Min. 95%

Color and Shape: White To Yellow Solid

Molecular weight: 112.11 g/mol

Ref: 3D-FA10596