CAS 944842-54-0

VX 509

Description:

VX 509, identified by its CAS number 944842-54-0, is a synthetic compound that belongs to a class of substances known as small molecule inhibitors. It is primarily studied for its potential therapeutic applications, particularly in the context of cancer treatment. VX 509 functions as a selective inhibitor of certain signaling pathways, which can influence cell proliferation and survival. The compound is characterized by its ability to modulate immune responses, making it a candidate for immunotherapy. Its chemical structure includes specific functional groups that contribute to its biological activity and selectivity. VX 509 has undergone various preclinical and clinical evaluations to assess its efficacy and safety profile. As with many investigational drugs, its development is subject to rigorous testing to determine optimal dosing, potential side effects, and overall therapeutic benefit. The ongoing research surrounding VX 509 reflects the broader interest in targeted therapies that can provide more effective treatment options with fewer side effects compared to traditional chemotherapy.

Formula: C₁₈H₁₉F₃N₆O

InChI: InChI=1S/C18H19F3N6O/c1-3-17(2,16(28)25-10-18(19,20)21)27-13-6-8-23-15(26-13)12-9-24-14-11(12)5-4-7-22-14/h4-9H,3,10H2,1-2H3,(H,22,24)(H,25,28)(H,23,26,27)/t17-/m1/s1

InChI key: InChIKey=ASUGUQWIHMTFJL-QGZVFWFLSA-N

SMILES: N([C@@](C(NCC(F)(F)F)=O)(CC)C)C1=NC(C=2C=3C(NC2)=NC=CC3)=NC=C1

Synonyms:

• (2R)-2-Methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]-N-(2,2,2-trifluoroethyl)butanamide
• (2R)-2-Methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-N-(2,2,2-trifluoroethyl)butanamide
• Adelatinib
• Butanamide, 2-methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)-4-pyrimidinyl]amino]-N-(2,2,2-trifluoroethyl)-, (2R)-
• V 509
• Vrt 831509
• Vx-509
• Decernotinib(VX-509)
• (R)-2-((2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)-2-methyl-N-(2,2,2-trifluoroethyl)butanamide
• Decernotinib

Decernotinib

CAS: 944842-54-0

Formula: C₁₈H₁₉F₃N₆O

Purity: 99%

Color and Shape: Solid

Molecular weight: 392.3783

Ref: IN-DA00II7R

Decernotinib

CAS: 944842-54-0

Decernotinib

Purity: ≥98%

Molecular weight: 392.38g/mol

Ref: 54-BUP07327

Decernotinib

CAS: 944842-54-0

Decernotinib (VRT-831509)(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays.

Formula: C₁₈H₁₉F₃N₆O

Purity: 99.28% - >99.99%

Color and Shape: Solid

Molecular weight: 392.38

Ref: TM-T2636

(R)-2-((2-(1H-Pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl)amino)-2-methyl-N-(2,2,2-trifluoroethyl)butanamide

CAS: 944842-54-0

Formula: C₁₈H₁₉F₃N₆O

Purity: 99%

Molecular weight: 392.386

Ref: 10-F496922

Decernotinib

Controlled Product

CAS: 944842-54-0

Formula: C₁₈H₁₉F₃N₆O

Color and Shape: Neat

Molecular weight: 392.378

Ref: TR-D225580