CAS 944904-42-1

3-Iodo-1H-indazole-6-carboxaldehyde

Description:

3-Iodo-1H-indazole-6-carboxaldehyde is a chemical compound characterized by its indazole core, which is a five-membered heterocyclic structure containing two nitrogen atoms. The presence of an aldehyde functional group at the 6-position and an iodine atom at the 3-position contributes to its reactivity and potential applications in organic synthesis and medicinal chemistry. This compound is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. Its structure allows for various chemical modifications, making it a valuable intermediate in the synthesis of more complex molecules. The iodine substituent can enhance the compound's biological activity and influence its interaction with biological targets. Additionally, the presence of the carboxaldehyde group may facilitate further reactions, such as condensation or reduction, expanding its utility in synthetic pathways. As with many halogenated compounds, safety precautions should be taken when handling 3-Iodo-1H-indazole-6-carboxaldehyde due to potential toxicity and reactivity.

Formula: C₈H₅IN₂O

InChI: InChI=1S/C8H5IN2O/c9-8-6-2-1-5(4-12)3-7(6)10-11-8/h1-4H,(H,10,11)

InChI key: InChIKey=LNFYGHSDBUEHAM-UHFFFAOYSA-N

SMILES: IC=1C=2C(=CC(C=O)=CC2)NN1

Synonyms:

• 3-Iodo-2H-indazole-6-carbaldehyde
• 1H-Indazole-6-carboxaldehyde, 3-iodo-
• 3-Iodo-1H-indazole-6-carboxaldehyde
• 3-Iodo-1H-indazole-6-carbaldehyde

3-Iodo-1H-Indazole-6-Carbaldehyde

CAS: 944904-42-1

Formula: C₈H₅IN₂O

Purity: 97%

Molecular weight: 272.0426

Ref: IN-DA00II9T

3-Iodo-1H-indazole-6-carbaldehyde

CAS: 944904-42-1

3-Iodo-1H-indazole-6-carbaldehyde

Purity: >98%

Molecular weight: 272.04g/mol

Ref: 54-OR948475

3-Iodo-1H-indazole-6-carbaldehyde

CAS: 944904-42-1

3-Iodo-1H-indazole-6-carbaldehyde (3IAA) is a novel indazole inhibitor that has been shown to inhibit tumor growth in vivo. 3IAA binds to the tumor and inhibits cancer cell proliferation by blocking the synthesis of DNA, RNA, and protein. The antitumor activity of 3IAA has been demonstrated in various animal models of cancer. 3IAA also inhibits angiogenesis, which is necessary for the development of a tumor's blood supply. This agent has been found to be bioavailable orally and shows anticancer efficacy in mice. Oral exposure to 3IAA induced a significant decrease in tumor volume and weight in mice bearing xenografts.

Formula: C₈H₅IN₂O

Purity: Min. 95%

Molecular weight: 272.04 g/mol

Ref: 3D-UMB90442