CAS 94535-50-9
:(-)-Cromakalim
Description:
(-)-Cromakalim is a chemical compound known for its role as a potassium channel opener, primarily affecting ATP-sensitive potassium channels. It is classified as a pharmacological agent and is often studied for its potential therapeutic applications, particularly in cardiovascular medicine. The compound exhibits vasodilatory effects, which can lead to the relaxation of smooth muscle and a decrease in vascular resistance. This mechanism makes it of interest in the treatment of conditions such as hypertension and angina. (-)-Cromakalim is typically characterized by its stereochemistry, as indicated by the prefix "(-)", which denotes its specific optical activity. The compound is soluble in organic solvents and has a relatively low molecular weight, contributing to its bioavailability. Its safety profile and pharmacokinetics are subjects of ongoing research, as understanding these characteristics is crucial for its potential clinical applications. Overall, (-)-Cromakalim represents a significant area of study in pharmacology, particularly in the context of cardiovascular health.
Formula:C16H18N2O3
InChI:InChI=1S/C16H18N2O3/c1-16(2)15(20)14(18-7-3-4-13(18)19)11-8-10(9-17)5-6-12(11)21-16/h5-6,8,14-15,20H,3-4,7H2,1-2H3/t14-,15+/m1/s1
InChI key:InChIKey=TVZCRIROJQEVOT-CABCVRRESA-N
SMILES:O[C@H]1[C@@H](C=2C(OC1(C)C)=CC=C(C#N)C2)N3C(=O)CCC3
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Found 5 products.
Levcromakalim
CAS:Levcromakalim (BRL 38227) is an activator of the ATP-sensitive K+ channel.Formula:C16H18N2O3Purity:99.74%Color and Shape:SolidMolecular weight:286.33Levcromakalim-d4
CAS:Controlled ProductFormula:C16H14D4N2O3Color and Shape:NeatMolecular weight:290.35Levcromakalim
CAS:<p>Inhibitor of ATP-sensitive potassium channels</p>Formula:C16H18N2O3Purity:Min. 95%Color and Shape:White/Off-White SolidMolecular weight:286.33 g/mol
