CAS 945414-97-1

6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH₂

CAS: 945414-97-1

NBD-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys(DMC)-NH₂ (NBD-RPKPLA-Nva-WK(DMC) amide) is an excellent fluorogenic substrate for hydrolysis of the matrix metalloproteinase stromelysin (MMP-3). This FRET substrate exhibits high sensitivity and improves accuracy at lower substrate turnover. It has a kcat/Km value of 2.14 x 10⁴ M⁻¹s⁻¹ and can be easily detected at 350 nm (excitation) and 465 nm (emission). Therefore this compound is a suitable tool for high-throughput inhibitor screening.

Formula: C₇₈H₁₁₁N₂₁O₁₆

Purity: 97.4%

Color and Shape: Orange Powder

Molecular weight: 1598.87

Ref: 01-4028275

6-(7-Nitro-benzo[2,1,3]oxadiazol-4-ylamino)-hexanoyl-Arg-Pro-Lys-Pro-Leu-Ala-Nva-Trp-Lys((7-dimethylaminocoumarin-4-yl)-acetyl)-NH2 trifluoroacetate salt

CAS: 945414-97-1

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Formula: C₇₈H₁₁₁N₂₁O₁₆

Purity: Min. 95%

Molecular weight: 1,598.85 g/mol

Ref: 3D-FN110943