CAS 945595-80-2

N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine

Description:

N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine, with CAS number 945595-80-2, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple aromatic rings and functional groups. This compound features a phthalazinamine core, which is linked to a thienyl group and a pyrimidinyl-pyridinyl moiety through an ether linkage. The presence of amino and methyl groups contributes to its potential biological activity. Typically, such compounds are investigated for their pharmacological properties, including their role as potential therapeutic agents in various diseases. The intricate arrangement of heteroatoms and functional groups suggests that it may exhibit specific interactions with biological targets, making it of interest in medicinal chemistry. Additionally, its solubility, stability, and reactivity would depend on the specific conditions and solvents used in experimental settings. Overall, this compound exemplifies the complexity often found in drug-like molecules, highlighting the interplay between structure and function in chemical biology.

Formula: C₂₈H₂₁N₇OS

InChI: InChI=1S/C28H21N7OS/c1-17-15-24(37-16-17)25-20-5-2-3-6-21(20)26(35-34-25)32-18-8-10-19(11-9-18)36-27-22(7-4-13-30-27)23-12-14-31-28(29)33-23/h2-16H,1H3,(H,32,35)(H2,29,31,33)

InChI key: InChIKey=IVUGFMLRJOCGAS-UHFFFAOYSA-N

SMILES: N(C=1C2=C(C(=NN1)C=3SC=C(C)C3)C=CC=C2)C4=CC=C(OC5=C(C=CC=N5)C6=NC(N)=NC=C6)C=C4

Synonyms:

• N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine
• 1-Phthalazinamine, N-[4-[[3-(2-amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-
• AMG 900

AMG 900

CAS: 945595-80-2

Formula: C₂₈H₂₁N₇OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 503.5776

Ref: IN-DA01DPYZ

N-(4-((3-(2-Aminopyrimidin-4-Yl)Pyridin-2-Yl)Oxy)Phenyl)-4-(4-Methylthiophen-2-Yl)Phthalazin-1-Amine

CAS: 945595-80-2

N-(4-((3-(2-Aminopyrimidin-4-Yl)Pyridin-2-Yl)Oxy)Phenyl)-4-(4-Methylthiophen-2-Yl)Phthalazin-1-Amine

Purity: 98%

Molecular weight: 503.58g/mol

Ref: 54-OR1023074

AMG 900

CAS: 945595-80-2

AMG 900

Purity: ≥98%

Molecular weight: 503.58g/mol

Ref: 54-BUP09334

AMG 900-d4

CAS: 945595-80-2

Formula: C₂₈H₁₇D₄N₇OS

Molecular weight: 507.61

Ref: 4Z-A-241002

AMG 900

CAS: 945595-80-2

Formula: C₂₈H₂₁N₇OS

Molecular weight: 503.58

Ref: 4Z-A-241001

AMG 900

CAS: 945595-80-2

AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM.

Formula: C₂₈H₂₁N₇OS

Purity: 98.4% - 99.51%

Color and Shape: Solid

Molecular weight: 503.58

Ref: TM-T6380