CAS 945667-22-1: Saxagliptin hydrate

Description: Saxagliptin hydrate is a pharmaceutical compound primarily used as an antidiabetic medication, specifically for the management of type 2 diabetes mellitus. It functions as a dipeptidyl peptidase-4 (DPP-4) inhibitor, which helps to increase insulin secretion and decrease glucagon levels in the bloodstream, thereby improving glycemic control. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for oral administration. Its molecular formula includes a specific arrangement of carbon, hydrogen, nitrogen, and oxygen atoms, contributing to its biological activity. Saxagliptin hydrate is typically administered in tablet form and may be used alone or in combination with other antidiabetic agents. As with any medication, it is essential to consider potential side effects, contraindications, and interactions with other drugs. The compound's stability and efficacy are influenced by factors such as pH and temperature, which are critical in pharmaceutical formulations.

Formula: C₁₈H₂₅N₃O₂·H₂O

InChI: InChI=1S/C18H25N3O2.H2O/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H2/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1

InChI key: InChIKey=AFNTWHMDBNQQPX-NHKADLRUSA-N

SMILES: N#CC1N(C(=O)C(N)C23CC4CC(CC(O)(C4)C2)C3)C5CC5C1.O

Synonyms:

• (1S,3S,5S)-2-((2S)-2-Amino-2-(3-Hydroxytricyclo(3.3.1.13,7)Dec-1-Yl)Acetyl)-2-Azabicyclo(3.1.0)Hexane-3-Carbonitrile Hydrate
• 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-amino-2-(3-hydroxytricyclo[3.3.1.1^3,7]dec-1-yl)acetyl]-, hydrate (1:1), (1S,3S,5S)-
• Saxagliptin hydrate
• 2-Azabicyclo[3.1.0]hexane-3-carbonitrile, 2-[(2S)-2-amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-, hydrate (1:1), (1S,3S,5S)-
• Saxagliptin monohydrate

Saxagliptin impurity mixture CRS

CAS: 945667-22-1

Saxagliptin monohydrate CRS

CAS: 945667-22-1

Saxagliptin

CAS: 945667-22-1

Heterocyclic compounds with nitrogen hetero-atom(s) only, excluding aromatic or modified aromatic

• Formula: C₁₈H₂₅N₃O₂·H₂O
• Color and Shape: White Off-White Light Brown Crystalline Powder
• Molecular weight: 333.20524

(1S,3S,5S)-2-[(2S)-2-Amino-2-(3-hydroxytricyclo[3.3.1.13,7]dec-1-yl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrate(1:1)

CAS: 945667-22-1

• Formula: C₁₈H₂₇N₃O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 333.4253

Saxagliptin hydrate

CAS: 945667-22-1

Saxagliptin hydrate (Onglyza hydrate) is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: …

• Formula: C₁₈H₂₅N₃O₂·H₂O
• Purity: 99.52%
• Color and Shape: Solid
• Molecular weight: 333.43

Saxagliptin Hydrate

CAS: 945667-22-1

• Purity: 98%
• Molecular weight: 333.43g/mol

Saxagliptin hydrate

CAS: 945667-22-1

• Purity: ≥98%
• Molecular weight: 333.43g/mol

Saxagliptin Hydrate

CAS: 945667-22-1

Applications Saxagliptin Hydrate is a selective and reversible dipeptidyl peptidase-4 (DPP4) inhibitor that may be …

• Formula: C₁₈H₂₅N₃O₂·H₂O
• Color and Shape: Neat
• Molecular weight: 333.43

Saxagliptin monohydrate

CAS: 945667-22-1

Dipeptidyl peptidase-4 inhibitor; anti-diabetic agent

• Formula: C₁₈H₂₅N₃O₂•H₂O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 333.43 g/mol