CAS 945755-56-6

XL019

Description:

XL019, with the CAS number 945755-56-6, is a small molecule inhibitor primarily developed for therapeutic applications in oncology. It functions as a selective inhibitor of certain kinases, particularly those involved in the signaling pathways that regulate cell proliferation and survival. This compound has shown promise in preclinical studies for its ability to inhibit tumor growth and induce apoptosis in cancer cells. Its mechanism of action typically involves the disruption of specific protein interactions and signaling cascades that are crucial for cancer cell viability. XL019 is characterized by its relatively low molecular weight and specific structural features that enhance its binding affinity to target proteins. Additionally, it is often evaluated for its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion (ADME), which are critical for determining its efficacy and safety profile in clinical settings. As research continues, XL019 may contribute to the development of targeted therapies for various malignancies, highlighting the importance of precision medicine in cancer treatment.

Synonyms:

• (S)-N-(4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)phenyl)pyrrolidine-2-carboxamide

Pyrrolidine-2-carboxylic acid {4-[2-(4-morpholin-4-yl-phenylamino)-pyrimidin-4-yl]-phenyl}-amide

CAS: 945755-56-6

Formula: C₂₅H₂₈N₆O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 444.5288

Ref: IN-DA01DMY0

XL019

CAS: 945755-56-6

XL019

Purity: ≥98%

Molecular weight: 444.53g/mol

Ref: 54-BUP06342

XL019

CAS: 945755-56-6

XL019 is a potent and selective JAK2 inhibitor with IC50 of 2.2 nM, 100 fold selectivity over JAK1.

Formula: C₂₅H₂₈N₆O₂

Purity: 99.19%

Color and Shape: Solid

Molecular weight: 444.53

Ref: TM-T3072

(2S)-N-[4-[2-[[4-(4-Morpholinyl)phenyl]amino]-4-pyrimidinyl]phenyl]-2-pyrrolidinecarboxamide

Controlled Product

CAS: 945755-56-6

Formula: C₂₅H₂₈N₆O₂

Color and Shape: Neat

Molecular weight: 444.529

Ref: TR-M725080