CAS 946249-82-7

2-(2-(3-Phenylureido)thiazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide

CAS: 946249-82-7

2-(2-(3-Phenylureido)thiazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide is a potent inhibitor of angiotensin II. It has been shown to inhibit the binding of the peptide angiotensin II to its receptor, and thus prevents the activation of a number of biological responses including vasoconstriction, release of renin from the kidneys, and increased blood pressure. This drug is structurally similar to captopril, but with a different functional group on the phenyl ring. 2-(2-(3-Phenylureido)thiazol-4-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide has also been shown to act as an inhibitor of ion channels that are involved in pain perception, such as voltage gated calcium channels.

Formula: C₁₉H₁₅F₃N₄O₃S

Purity: Min. 95%

Molecular weight: 436.4 g/mol

Ref: 3D-WMB24982

CU239

CAS: 946249-82-7

CU239 is a selective non-retinoid inhibitor of RPE65 which suppresses visual cycle and prevents retinal degeneration.

Formula: C₁₉H₁₅F₃N₄O₃S

Color and Shape: Solid

Molecular weight: 436.41

Ref: TM-T71715