CAS 946682-32-2

3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4,4-dimethylpentanoic acid

Description:

3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4,4-dimethylpentanoic acid, commonly referred to as Fmoc-Dmp-Asp, is a synthetic amino acid derivative used primarily in peptide synthesis and drug development. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under acidic conditions. The presence of the dimethylpentanoic acid moiety contributes to its hydrophobic characteristics, influencing the solubility and interaction of the compound in biological systems. The structure includes an amino group, which is essential for peptide bond formation, and a carboxylic acid group, which plays a critical role in the acid-base chemistry of the molecule. Overall, this compound is valued for its utility in creating complex peptides and proteins, facilitating research in biochemistry and medicinal chemistry. Its CAS number, 946682-32-2, uniquely identifies it in chemical databases, aiding in the retrieval of information regarding its properties and applications.

Formula: C₂₂H₂₅NO₄

InChI: InChI=1S/C22H25NO4/c1-22(2,3)19(12-20(24)25)23-21(26)27-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,23,26)(H,24,25)

InChI key: InChIKey=OZJGKTWSHFVPPN-UHFFFAOYSA-N

SMILES: C(OC(NC(CC(O)=O)C(C)(C)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• 3-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-4,4-dimethylpentanoic acid
• Pentanoic acid, 3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-4,4-dimethyl-
• 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4,4-dimethylpentanoic acid
• (R,S)-Fmoc-3-(t-butyl)-β-ala-oh