CAS 946846-83-9

Piromelatine

Description:

Piromelatine is a synthetic compound that functions primarily as a melatonergic agent, influencing the melatonin receptors in the brain. It is characterized by its potential use in the treatment of sleep disorders and its role in regulating circadian rhythms. The substance is known for its ability to promote sleep and improve sleep quality, making it a subject of interest in sleep medicine. Piromelatine exhibits a unique pharmacological profile, differentiating it from traditional melatonin supplements by potentially offering a more targeted action with fewer side effects. Its chemical structure includes specific functional groups that contribute to its activity at melatonin receptors, particularly MT1 and MT2. Additionally, research into piromelatine has explored its neuroprotective properties, suggesting it may have applications beyond sleep regulation, including potential benefits in mood disorders and neurodegenerative conditions. As with any pharmacological agent, further studies are essential to fully understand its efficacy, safety, and long-term effects in various populations.

Formula: C₁₇H₁₆N₂O₄

InChI: InChI=1S/C17H16N2O4/c1-22-13-2-3-15-14(9-13)11(10-19-15)4-6-18-17(21)16-8-12(20)5-7-23-16/h2-3,5,7-10,19H,4,6H2,1H3,(H,18,21)

InChI key: InChIKey=PNTNBIHOAPJYDB-UHFFFAOYSA-N

SMILES: C(CNC(=O)C1=CC(=O)C=CO1)C=2C=3C(NC2)=CC=C(OC)C3

Synonyms:

• 4H-Pyran-2-carboxamide, N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-4-oxo-
• Piromelatine
• N-[2-(5-Methoxy-1H-indol-3-yl)ethyl]-4-oxo-4H-pyran-2-carboxamide
• Neu-P 11

Piromelatine

CAS: 946846-83-9

Piromelatine

Purity: ≥98%

Molecular weight: 312.32g/mol

Ref: 54-BUP02657

Piromelatine

CAS: 946846-83-9

Piromelatine is a peptide that has been shown to activate ion channels in the central nervous system. It is used as a research tool and in studies of antibody-receptor interactions. Piromelatine has also been shown to inhibit protein interactions. The molecular weight of piromelatine is 554.5 Da, with a CAS number of 946846-83-9.

Formula: C₁₇H₁₆N₂O₄

Purity: Min. 95%

Molecular weight: 312.32 g/mol

Ref: 3D-WMB84683

Piromelatine

CAS: 946846-83-9

Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity with

Formula: C₁₇H₁₆N₂O₄

Purity: 99.83%

Color and Shape: Solid

Molecular weight: 312.32

Ref: TM-T34081