CAS 947331-05-7
:Allisartan Isoproxil
Description:
Allisartan Isoproxil is an angiotensin II receptor antagonist, primarily used in the treatment of hypertension. It functions by blocking the action of angiotensin II, a hormone that constricts blood vessels, thereby promoting vasodilation and reducing blood pressure. This compound is characterized by its prodrug nature, meaning it is metabolized in the body to its active form, which exerts the therapeutic effects. Allisartan Isoproxil is typically administered orally and is known for its favorable pharmacokinetic profile, including good bioavailability and a relatively long half-life, allowing for once-daily dosing. The substance is also noted for its selectivity towards the AT1 receptor, minimizing potential side effects associated with non-selective antagonists. In addition to its antihypertensive properties, research is ongoing to explore its potential benefits in other cardiovascular conditions. As with any medication, it is essential to consider contraindications and potential interactions with other drugs when prescribing Allisartan Isoproxil.
Formula:C27H29ClN6O5
Synonyms:- Losartan Impurity 19（Allisartan Isoproxil）
- 1H-Imidazole-5-carboxylic acid, 2-butyl-4-chloro-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, [[(1-methylethoxy)carbonyl]oxy]methyl ester
- Allisartan
- Allisartan Isoproxil
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