CAS 94744-50-0

2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-2-methylpropionic acid

Description:

2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-2-methylpropionic acid, commonly referred to as Fmoc-amino acid, is a chemical compound used primarily in peptide synthesis and as a protecting group for amino acids. This compound features a fluorenylmethoxycarbonyl (Fmoc) group, which is a popular protective group due to its stability under basic conditions and ease of removal under mild acidic conditions. The structure includes a branched side chain with a methyl group, contributing to its steric properties. It is typically a white to off-white solid and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dimethylformamide (DMF), but less soluble in water. The presence of the carboxylic acid functional group allows it to participate in various chemical reactions, making it versatile in synthetic organic chemistry. Its CAS number, 94744-50-0, is unique to this compound, facilitating its identification in chemical databases and literature. Overall, this compound is significant in the field of biochemistry and pharmaceutical development.

Formula: C₁₉H₁₉NO₄

InChI: InChI=1/C19H19NO4/c1-19(20,18(22)23)10-17(21)24-11-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,16H,10-11,20H2,1H3,(H,22,23)

InChI key: InChIKey=HOZZVEPRYYCBTO-UHFFFAOYSA-N

SMILES: C(OC(NC(C(O)=O)(C)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• 2-(9H-Fluoren-9-ylmethoxycarbonylamino)-2-methylpropanoic acid
• 2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-2-methylpropanoic acid
• 2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-2-methylpropanoic acid
• 2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-2-methylpropionic acid
• Alanine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-methyl-
• Fmoc-2-Amino-2-methylpropionic acid
• Fmoc-2-aminoisobutyric acid
• Fmoc-Aib-OH
• Fmoc-alpha-Me-Ala-OH
• N-9-Fluorenylmethoxycarbonyl-α-aminoisobutyric acid
• N-Fmoc-2-aminoisobutyric acid
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-2-methylalanine
• FMOC-ALPHA-METHYLALANINE
• FMOC-(ME)ALA-OH
• N-ALPHA-FMOC-L-ALPHA-AMINOISOBUTYRIC ACID
• BOC-3-IODO-ALA-OME
• NALPHA-9-Fluorenylmethoxycarbonyl-2-aminoisobutyric acid
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-ISOBUTYRIC ACID, FMOC-ALPHA-METHYL-ALANINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-ALPHA-METHYL-L-ALANINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-ALPHA-AMINOISOBUTYRIC ACID
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-AMINOISOBUTYRIC ACID
• 2-(9h-fluoren-9-ylmethoxycarbonylamino)-2-methyl-propanoic acid
• fmoc-α-aminoisobutyric acid
• N-α-Fmoc-α-aminoisobutyricacid
• N-ALPHA-FMOC-ALPHA-AMINOISOBUTYRIC ACID
• RARECHEM EM WB 0053
• FMOC-ALPHA-AMINOISOBUTYRIC ACID

2-[(9H-Fluoren-9-ylmethoxy)carbonylamino]isobutyric Acid

CAS: 94744-50-0

Formula: C₁₉H₁₉NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 325.36

Ref: 3B-F0888

2-(Fmoc-amino)isobutyric acid, 98%

CAS: 94744-50-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₉H₁₉NO₄

Purity: 98%

Molecular weight: 325.36

Ref: 02-H62211

Fmoc-Aib-OH

CAS: 94744-50-0

The acid fluoride of this sterically hindered amino acid could be coupled to N-methylated amino acids in HFIP at 55°C.

Formula: C₁₉H₁₉NO₄

Purity: 99.81%

Color and Shape: White

Molecular weight: 325.36

Ref: 01-4013932

Fmoc-Aib-OH

CAS: 94744-50-0

Formula: C₁₉H₁₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 325.3585

Ref: IN-DA0068HP

Fmoc-α-Methylalanine

CAS: 94744-50-0

Fmoc-α-Methylalanine

Purity: 98%

Molecular weight: 325.36g/mol

Ref: 54-OR1013330

Fmoc-α-Me-Ala-OH

CAS: 94744-50-0

Formula: C₁₉H₁₉NO₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 325.36

Ref: 7W-GM0758

Fmoc-Aib-OH

CAS: 94744-50-0

Fmoc-Aib-OH (Fmoc-alpha-methylalanine) is an alanine acid derivative, which can be used for peptide synthesis and biopharmaceutical design.

Formula: C₁₉H₁₉NO₄

Purity: 99.59%

Color and Shape: Solid

Molecular weight: 325.36

Ref: TM-T66848

fmoc-aib-oh

CAS: 94744-50-0

Formula: C₁₉H₁₉NO₄

Purity: 98%

Color and Shape: Solid, Crystalline Powder or Powder

Molecular weight: 325.364

Ref: 10-F045381

Fmoc-α-methylalanine

CAS: 94744-50-0

Fmoc-alpha-methylalanine is a synthetic amino acid that can be used as an anticancer agent. It has been shown to inhibit the growth of prostate cancer cells and induce cell death by inhibiting protein synthesis. Fmoc-alpha-methylalanine has also been shown to have antimicrobial activity against Gram-positive bacteria, such as Staphylococcus aureus, and Gram-negative bacteria, such as Escherichia coli. This drug is synthesized from a grignard reagent with carbon nanotubes and 2-aminoisobutyric acid. The biphenyl group on the alpha position of the side chain serves as a fluorescence probe for detection in biological systems.

Formula: C₁₉H₁₉NO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 325.36 g/mol

Ref: 3D-FF45452