CAS 947502-66-1

5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

Description:

The chemical substance known as 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one, with the CAS number 947502-66-1, is a complex organic compound characterized by its unique structural features. It contains a thieno[3,2-c]pyridinone core, which is a bicyclic structure that incorporates both sulfur and nitrogen atoms, contributing to its potential biological activity. The presence of a cyclopropyl group and a fluorophenyl moiety suggests that the compound may exhibit interesting pharmacological properties, possibly influencing its interaction with biological targets. The hydroxyl group at the 7a position may enhance solubility and reactivity, while the oxoethyl substituent could play a role in its overall stability and reactivity. This compound is likely to be of interest in medicinal chemistry, particularly in the development of new therapeutic agents, due to its structural complexity and potential for diverse biological interactions. Further studies would be necessary to elucidate its specific properties and applications.

Formula: C₁₈H₁₈FNO₃S

Synonyms:

• Prasugrel impurity F
• 5-(2-CYCLOPROPYL-1-(2-FLUOROPHENYL)-2-OXOETHYL)-5,6,7,7A-TETRAHYDRO-7A-HYDROXYTHIENO[3,2-C]PYRIDIN-2(4H)-ONE
• Prasugrel Hydroxy Thiolactone
• Prasugrel EP Impurity F
• Prasugrel impurity 5/Prasugrel Hydroxy Thiolactone/5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
• Thieno[3,2-c]pyridin-2(4H)-one, 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-5,6,7,7a-tetrahydro-7a-hydroxy-
• Desacetyl hydroxyprasugrel
• Prasugrel impurities1182
• 5-(2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one
• 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-7a-hydroxy-6,7-dihydro-4H-thieno[3,2-c]pyridin-2-one

5-(2-Cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl)-7a-hydroxy-5,6,7,7a-tetrahydrothieno[3,2-c]pyridin-2(4H)-one

CAS: 947502-66-1

Formula: C₁₈H₁₈FNO₃S

Color and Shape: Solid

Molecular weight: 347.4038

Ref: IN-DA00III8

Prasugrel EP Impurity F

CAS: 947502-66-1

Formula: C₁₈H₁₈FNO₃S

Molecular weight: 347.40

Ref: 4Z-P-3931

Prasugrel Hydroxy Thiolactone

Controlled Product

CAS: 947502-66-1

Applications Prasugrel Hydroxy Thiolactone, is the metabolite of Prasugrel (P701150), which is a novel thienopyridine. It is also a potent inhibitor of platelet aggregation in vivo.
References Von Beckerath, N., et al.: Circulation, 112, 2946 (2005), Jernberg, T., et al.: Eur. Heart J., 27, 1166 (2006), Farid, N., et al.: Drug Metab. Dispos., 35, 1096 (2007), Farid, N., et al.: Clin. Pharmacol. Ther., 81, 735 (2007), Jakubowski, J., et al.: J. Cardiovasc. Pharmacol., 49, 167 (2007), Wiviott, S., et al.: N. Engl. J. Med., 357, 2001 (2007),

Formula: C₁₈H₁₈FNO₃S

Color and Shape: Neat

Molecular weight: 347.4

Ref: TR-P701160

Prasugrel hydroxy thiolactone

CAS: 947502-66-1

Prasugrel hydroxy thiolactone is a drug product, analytical and Metabolism studies. It is an impurity standard for Synthetic, Custom synthesis, Drug development, Research and Development of Impurity standard. Prasugrel hydroxy thiolactone is synthesized by acid-catalyzed condensation of 2-aminothiophenol with acetyl chloride in the presence of zinc chloride. The resulting compound can be purified by recrystallization from ethanol/ether or extraction with diethyl ether.
Prasugrel hydroxy thiolactone has been used as a reference material for HPLC standards and pharmacopoeia.

Formula: C₁₈H₁₈FNO₃S

Purity: Min. 95%

Molecular weight: 347.4 g/mol

Ref: 3D-XMB50266

Prasugrel EP Impurity F

CAS: 947502-66-1

Formula: C₁₈H₁₈FNO₃S

Molecular weight: 347.4

Ref: ST-EA-CP-P27095