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CAS 947533-41-7

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[4-(trifluoromethyl)-3-pyridyl]boronic acid

Description:
[4-(Trifluoromethyl)-3-pyridyl]boronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a pyridine ring that has a trifluoromethyl substituent. This compound typically exhibits properties such as high stability under ambient conditions, making it suitable for various applications in organic synthesis and medicinal chemistry. The trifluoromethyl group enhances its lipophilicity and can influence its reactivity and biological activity. Boronic acids are known for their ability to form reversible covalent bonds with diols, which is significant in the development of sensors and drug delivery systems. Additionally, this compound can participate in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds, which is crucial in the synthesis of complex organic molecules. Its unique electronic properties, derived from the electron-withdrawing trifluoromethyl group, can also affect its interaction with biological targets, making it a compound of interest in pharmaceutical research. Overall, [4-(trifluoromethyl)-3-pyridyl]boronic acid is a versatile building block in synthetic chemistry.
Formula:C6H5BF3NO2
InChI:InChI=1/C6H5BF3NO2/c8-6(9,10)4-1-2-11-3-5(4)7(12)13/h1-3,12-13H
SMILES:c1cncc(c1C(F)(F)F)B(O)O
Synonyms:
  • [4-(Trifluoromethyl)pyridin-3-yl]boronic acid
  • boronic acid, B-[4-(trifluoromethyl)-3-pyridinyl]-
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