CAS 94841-17-5

Spirapril Hydrochloride

Description:

Spirapril hydrochloride is a pharmaceutical compound primarily used as an antihypertensive agent. It belongs to the class of drugs known as angiotensin-converting enzyme (ACE) inhibitors, which function by inhibiting the enzyme responsible for converting angiotensin I to angiotensin II, a potent vasoconstrictor. This action leads to vasodilation, reduced blood pressure, and decreased workload on the heart. Spirapril is characterized by its ability to improve cardiovascular outcomes in patients with hypertension and heart failure. The hydrochloride salt form enhances its solubility and stability, making it suitable for oral administration. Common side effects may include dizziness, cough, and elevated potassium levels, which are typical of ACE inhibitors. Spirapril is often prescribed in conjunction with other antihypertensive medications to achieve optimal blood pressure control. As with all medications, it is essential to monitor patients for potential adverse effects and interactions with other drugs.

Formula: C₂₂H₃₀N₂O₅S₂·HCl

InChI: InChI=1/C22H30N2O5S2.ClH/c1-3-29-21(28)17(10-9-16-7-5-4-6-8-16)23-15(2)19(25)24-14-22(30-11-12-31-22)13-18(24)20(26)27;/h4-8,15,17-18,23H,3,9-14H2,1-2H3,(H,26,27);1H/t15-,17-,18-;/m0./s1

SMILES: CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CC2(C[C@H]1C(=O)O)SCCS2.Cl

Synonyms:

• Spirapril hydrochloride [USAN]
• (8S)-7((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)-1,4-dithia-7-azaspiro(4.4)nonane-8-carboxylic acid, 1-ethyl ester, monohydrochloride
• 1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid, 7-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, monohydrochloride, (8S-(7(R*(R*)),8R*))-
• Renormax
• Sch 33844
• Spirapril HCl
• Unii-Occ25Lm897
• (8S)-7-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid hydrochloride (non-preferred name)
• Spirapril hydrochloride
• Sandopril
• Renpress
• TI 211-950

SPIRAPRIL HYDROCHLORIDE MONOHYDRATE CRS

CAS: 94841-17-5

SPIRAPRIL HYDROCHLORIDE MONOHYDRATE CRS

Formula: C₂₂H₃₁ClN₂O₅S₂

Molecular weight: 503.0749

Ref: 41-Y0000381

SPIRAPRIL FOR SYSTEM SUITABILITY CRS

CAS: 94841-17-5

SPIRAPRIL FOR SYSTEM SUITABILITY CRS

Formula: C₂₂H₃₁ClN₂O₅S₂

Molecular weight: 503.0749

Ref: 41-Y0000332

Spirapril Hydrochloride

CAS: 94841-17-5

Formula: C₂₂H₃₀N₂O₅S₂·ClH

Color and Shape: White To Off-White

Molecular weight: 503.07

Ref: TR-S682500

Spirapril hydrochloride

CAS: 94841-17-5

Spirapril hydrochloride is an antihypertensive agent, which is a synthetic pharmaceutical compound designed to treat high blood pressure. The compound is derived from laboratory synthesis aimed at modulating the renin-angiotensin-aldosterone system. Its mode of action involves the inhibition of angiotensin-converting enzyme (ACE), which is crucial for the conversion of angiotensin I to the vasoconstrictor peptide angiotensin II. Angiotensin II is responsible for the constriction of blood vessels and an increase in blood pressure. By inhibiting this enzyme, Spirapril hydrochloride effectively reduces vascular resistance and lowers blood pressure.

Formula: C₂₂H₃₀N₂O₅S₂•HCl

Purity: Min. 95%

Molecular weight: 503.08 g/mol

Ref: 3D-BS183296