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CAS 948566-12-9

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Fluticasone 17beta-Carbonylsulfenic Acid 17-Propionate

Description:
Fluticasone 17beta-Carbonylsulfenic Acid 17-Propionate is a synthetic corticosteroid with anti-inflammatory properties, primarily used in the treatment of respiratory conditions such as asthma and allergic rhinitis. This compound is characterized by its glucocorticoid activity, which helps in reducing inflammation and suppressing the immune response. It features a propionate ester group, enhancing its lipophilicity and facilitating better absorption when administered via inhalation or topical routes. The chemical structure includes a carbonyl sulfenic acid moiety, which contributes to its pharmacological profile. Fluticasone is known for its high potency and relatively low systemic bioavailability, minimizing potential side effects associated with corticosteroids. Its mechanism of action involves the modulation of gene expression, leading to decreased production of pro-inflammatory cytokines and other mediators. Overall, Fluticasone 17beta-Carbonylsulfenic Acid 17-Propionate is an important therapeutic agent in managing chronic inflammatory conditions, providing effective relief with a favorable safety profile when used as directed.
Formula:C24H30F2O6S
Synonyms:
  • [(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11-hydroxy-17-hydroxysulfanylcarbonyl-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
  • Flutione sulfenic acid propionate
  • Unii-33Ueq4E893
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