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CAS 94885-02-6

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N-(NBD-Aminohexanoyl)-D-erythro-sphingosine

Description:
N-(NBD-Aminohexanoyl)-D-erythro-sphingosine is a synthetic derivative of sphingosine, a key component of sphingolipids, which are important in cell membrane structure and signaling. This compound features a NBD (nitrobenzoxadiazole) moiety, which is often used as a fluorescent tag, allowing for visualization and tracking in biological studies. The aminohexanoyl group enhances solubility and may facilitate cellular uptake. Characteristically, this compound exhibits amphiphilic properties due to its hydrophobic sphingosine backbone and hydrophilic NBD and aminohexanoyl groups, making it suitable for incorporation into lipid bilayers or micelles. It is primarily utilized in biochemical research, particularly in studies involving lipid metabolism, cell signaling, and membrane dynamics. The presence of the NBD group allows for fluorescence-based assays, enabling researchers to monitor interactions and localization within cellular environments. As with many sphingolipid derivatives, it may also play a role in modulating cellular processes such as apoptosis and inflammation. Proper handling and storage are essential due to its chemical nature and potential biological activity.
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