CAS 94944-80-6

3,3′-[[4-(1,1-Dimethylethyl)phenyl]methylene]bis[1H-indole]

Description:

3,3′-[[4-(1,1-Dimethylethyl)phenyl]methylene]bis[1H-indole], identified by its CAS number 94944-80-6, is an organic compound characterized by its complex structure, which includes two indole units linked by a methylene bridge and a tert-butyl-substituted phenyl group. This compound typically exhibits properties associated with indole derivatives, such as potential biological activity and fluorescence. The presence of the tert-butyl group enhances its lipophilicity, which may influence its solubility and interaction with biological membranes. Additionally, the indole moiety is known for its role in various biochemical processes and can serve as a precursor to numerous pharmaceuticals. The compound may also display interesting optical properties due to its conjugated system, making it a candidate for applications in materials science and organic electronics. Overall, 3,3′-[[4-(1,1-Dimethylethyl)phenyl]methylene]bis[1H-indole] represents a unique structure with potential utility in both medicinal chemistry and materials research.

Formula: C₂₇H₂₆N₂

InChI: InChI=1S/C27H26N2/c1-27(2,3)19-14-12-18(13-15-19)26(22-16-28-24-10-6-4-8-20(22)24)23-17-29-25-11-7-5-9-21(23)25/h4-17,26,28-29H,1-3H3

InChI key: InChIKey=NCPVEZRBHNDCIV-UHFFFAOYSA-N

SMILES: C(C=1C=2C(NC1)=CC=CC2)(C=3C=4C(NC3)=CC=CC4)C5=CC=C(C(C)(C)C)C=C5

Synonyms:

• 3,3′-((4-(tert-butyl)phenyl)methylene)bis(1H-indole)
• SML 0363
• 1,1-Bis(3′-indolyl)-1-(p-t-butylphenyl)methane
• 3,3′-[[4-(1,1-Dimethylethyl)phenyl]methylene]bis[1H-indole]
• 1H-Indole, 3,3′-[[4-(1,1-dimethylethyl)phenyl]methylene]bis-
• 3,3'-[(4-tert-butylphenyl)methanediyl]bis(1H-indole)
• 3-[(4-tert-butylphenyl)-(1H-indol-3-yl)methyl]-1H-indole
• DIM-C-pPhtBu
• 3,3'-(4-tert-Butylbenzylidene)bis(1H-indole)

Dim-C-pphtbu

CAS: 94944-80-6

Dim-C-pphtbu is a growth factor that has been shown to induce autophagy and inhibit cell proliferation. It was originally identified as a homologous protein to the human protein PHLDA2, which is involved in the regulation of angiogenesis. Dim-C-pphtbu was found to be expressed in cervical cancer cells and has been shown to inhibit the growth of these cells by inducing cell cycle arrest and apoptosis. This compound also inhibits the production of pro-angiogenic factors such as VEGF. Dim-C-pphtbu has been shown to have antiangiogenic effects in animal models of breast cancer and prostate cancer. Dim-C-pphtbu may be a potential drug repositioning candidate for p21 inhibition.

Formula: C₂₇H₂₆N₂

Purity: Min. 95%

Molecular weight: 378.5 g/mol

Ref: 3D-UDA94480