CAS 94948-59-1
:tumor necrosis factor human recombinant produced
Description:
Tumor necrosis factor (TNF), specifically the human recombinant form, is a cytokine involved in systemic inflammation and is part of the body's immune response. The substance with the CAS number 94948-59-1 is a recombinant version of TNF-alpha, produced using recombinant DNA technology. This protein is primarily secreted by macrophages and plays a crucial role in regulating immune cells, inducing fever, and promoting inflammation. It is characterized by its ability to induce apoptosis in certain cell types, stimulate the acute phase response, and enhance the activity of other immune mediators. TNF-alpha is also implicated in various pathological conditions, including autoimmune diseases, cancer, and chronic inflammatory disorders. As a therapeutic agent, it has been studied for its potential in treating malignancies and other diseases characterized by excessive inflammation. However, its use must be carefully managed due to potential side effects, including systemic inflammatory responses. Overall, TNF-alpha is a vital component of the immune system with significant implications for both health and disease.
Formula:C28H21Cl3N6O9
InChI:InChI=1/C15H16Cl3N3O2.C13H5N3O7/c1-2-4-20(15(22)21-5-3-19-10-21)6-7-23-14-12(17)8-11(16)9-13(14)18;17-13-9-3-6(14(18)19)1-2-8(9)12-10(13)4-7(15(20)21)5-11(12)16(22)23/h3,5,8-10H,2,4,6-7H2,1H3;1-5H
SMILES:CCCN(CCOc1c(cc(cc1Cl)Cl)Cl)C(=O)n1ccnc1.c1cc2c(cc1N(=O)=O)C(=O)c1cc(cc(c21)N(=O)=O)N(=O)=O
Synonyms:- Tumor Necrosis Factor-a, Human, Recomb.
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Found 2 products.
TNF α Human
CAS:TNF-α is a cytokine that has been shown to be a potent inducer of tumor necrosis. It also promotes the activation of macrophages, neutrophils, and endothelial cells. TNF-α is produced by many different cell types, but most notably by activated macrophages and lymphocytes. TNF-α is secreted from these cells in response to stimulation with lipopolysaccharide or other agents such as LPS, IL1β, or CD40 ligand. The protein encoded by this gene is an important cytokine for the immune system.
Purity:Min. 95%
