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CAS 949892-09-5

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B-(5-Chloro-4-fluoro-2-methoxyphenyl)boronic acid

Description:
B-(5-Chloro-4-fluoro-2-methoxyphenyl)boronic acid is an organoboron compound characterized by the presence of a boronic acid functional group attached to a substituted phenyl ring. This compound features a chloro and a fluoro substituent, as well as a methoxy group, which contribute to its unique chemical properties and reactivity. The boronic acid moiety is known for its ability to form reversible covalent bonds with diols, making it useful in various applications, including organic synthesis and medicinal chemistry. The presence of electron-withdrawing groups, such as chlorine and fluorine, can influence the acidity of the boronic acid and its reactivity in cross-coupling reactions, such as Suzuki coupling. Additionally, the methoxy group can enhance solubility and stability in organic solvents. Overall, this compound is of interest in the development of pharmaceuticals and agrochemicals, where its reactivity and functionalization potential can be exploited for the synthesis of complex molecules.
Formula:C7H7BClFO3
InChI:InChI=1S/C7H7BClFO3/c1-13-7-3-6(10)5(9)2-4(7)8(11)12/h2-3,11-12H,1H3
InChI key:InChIKey=MROIVWKVBXFEMP-UHFFFAOYSA-N
SMILES:B(O)(O)C1=C(OC)C=C(F)C(Cl)=C1
Synonyms:
  • Boronic acid, B-(5-chloro-4-fluoro-2-methoxyphenyl)-
  • (5-Chloro-4-fluoro-2-methoxyphenyl)boronic acid
  • B-(5-Chloro-4-fluoro-2-methoxyphenyl)boronic acid
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