ReModelin, identified by the CAS number 949912-58-7, is a synthetic compound that has garnered attention in the field of medicinal chemistry. While specific details about its characteristics may vary, it is generally recognized for its potential applications in therapeutic contexts, particularly in the modulation of biological pathways. The compound's structure likely includes functional groups that contribute to its biological activity, although precise structural information is not widely available. ReModelin may exhibit properties such as solubility in organic solvents, stability under certain conditions, and the ability to interact with specific biological targets, which could include enzymes or receptors. Its pharmacokinetic profile, including absorption, distribution, metabolism, and excretion, would be critical for understanding its efficacy and safety in potential therapeutic applications. As research continues, further insights into its mechanism of action and potential uses in clinical settings are anticipated.

Progeria is a genetic disorder that results in the appearance of premature aging. Genetically, progeria is characterized by a mutation in lamin A, which results in misshapen cell nuclei and DNA damage. Remodelin is a 2-thiazolylhydrazone derivative that, at 10 μM, improves nuclear architecture, chromatin organization, and survival of both cells lacking lamin A and cells from patients with progeria. Remodelin is an inhibitor of N-acetyltransferase 10 (NAT10), which acetylates both histones and microtubules. Mutation of NAT10 mimics the effects of remodelin on nuclear morphology, suggesting that these effects of remodelin require NAT10. Remodelin also has cytotoxic effects against some species of the fungus
Candida
.

ReModelin

949912-58-7: ReModelin, identified by the CAS number 949912-58-7, is a synthetic compound that has garnered attention in the field of medicinal chemistry. While specific details about its characteristics may vary, it is generally recognized for its potential applications in therapeutic contexts, particularly in the modulation of biological pathways. The compound's structure likely includes functional groups that contribute to its biological activity, although precise structural information is not widely available. ReModelin may exhibit properties such as solubility in organic solvents, stability under certain conditions, and the ability to interact with specific biological targets, which could include enzymes or receptors. Its pharmacokinetic profile, including absorption, distribution, metabolism, and excretion, would be critical for understanding its efficacy and safety in potential therapeutic applications. As research continues, further insights into its mechanism of action and potential uses in clinical settings are anticipated.

Remodelin

Remodelin is an effective and specific inhibitor of the acetyl-transferase protein NAT10.

CAS 949912-58-7

ReModelin

Remodelin

Ref: IN-DA01DNT6

Remodelin

Ref: 54-BUP15590

Remodelin

Ref: TM-T3499