CAS 95-20-5

2-Methylindole

Description:

2-Methylindole, with the CAS number 95-20-5, is an organic compound that belongs to the indole family, characterized by a bicyclic structure consisting of a benzene ring fused to a pyrrole ring. This compound features a methyl group attached to the second carbon of the indole structure, which influences its chemical properties and reactivity. 2-Methylindole is typically a colorless to pale yellow liquid with a distinctive odor. It is moderately soluble in water and more soluble in organic solvents, reflecting its hydrophobic nature. The compound exhibits basic properties due to the presence of the nitrogen atom in the indole ring, allowing it to participate in various chemical reactions, including electrophilic substitutions and nucleophilic attacks. 2-Methylindole is of interest in various fields, including pharmaceuticals and agrochemicals, due to its potential biological activities. Additionally, it can be synthesized through several methods, including the methylation of indole. Safety data indicates that it should be handled with care, as it may pose health risks upon exposure.

Formula: C₉H₉N

InChI: InChI=1S/C9H9N/c1-7-6-8-4-2-3-5-9(8)10-7/h2-6,10H,1H3

InChI key: InChIKey=BHNHHSOHWZKFOX-UHFFFAOYSA-N

SMILES: CC1=CC=2C(N1)=CC=CC2

Synonyms:

• 2-Methyl-1H-indole
• 2-Methylindol
• 2-Methylindole
• 2-Metilindol
• Indole, 2-Methyl-
• Nsc 7514
• 1H-Indole, 2-methyl-

2-Methylindole

CAS: 95-20-5

Formula: C₉H₉N

Purity: >99.0%(GC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 131.18

Ref: 3B-M0346

2-Methylindole, 98+%

CAS: 95-20-5

2-Methylindole is used as a reactant for regioselective synthesis of oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition reaction, Friedel-Crafts alkylation reactions, preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators, Mich

Formula: C₉H₉N

Purity: 98+%

Color and Shape: Crystals or crystalline powder or granules or flakes, Yellow to red-purple to brown or purple

Molecular weight: 131.18

Ref: 02-A10764

2-Methylindole

CAS: 95-20-5

Formula: C₉H₉N

Purity: 98%

Color and Shape: Solid

Molecular weight: 131.1745

Ref: IN-DA003HPJ

2-Methyl-1H-indole

CAS: 95-20-5

2-Methyl-1H-indole

Purity: 99%

Molecular weight: 131.17g/mol

Ref: 54-OR10174

2-Methylindole

CAS: 95-20-5

Formula: C₉H₉N

Purity: ≥ 98.0%

Color and Shape: White to yellow or brown powder, crystals or flakes

Molecular weight: 131.18

Ref: 7W-GK3342

2-Methylindole

CAS: 95-20-5

Color and Shape: Neat

Ref: 86-MM0477.06

2-Methylindole

Controlled Product

CAS: 95-20-5

Applications 2-Methylindole is an intermediate in the synthesis of indole derivative with potential antifungal activities.
References Rodriguez, S., et al.: Natural. Prod. Res., 22, 253 (2008); Zhang, B.G., et al.: Bioresource., 100, 5687 (2009);

Formula: C₉H₉N

Color and Shape: Neat

Molecular weight: 131.1745

Ref: TR-M313450

2-Methylindole

CAS: 95-20-5

2-Methylindole is a reactive molecule that can undergo electrophilic substitution at the 2-position. It reacts with a variety of nitrogen nucleophiles, acylating them at the 2-position. These reactions are catalyzed by enzymes such as carbonyl reductase and methyl ketone reductase. The reaction mechanism is not yet fully understood, but it has been proposed that it proceeds through an acylation reaction between two molecules of 2-methylindole to form a linear product. The regiospecificity of this reaction has been demonstrated in vivo using a model system.

Formula: C₉H₉N

Color and Shape: Powder

Molecular weight: 131.17 g/mol

Ref: 3D-FM02013

2-Methylindole

CAS: 95-20-5

Formula: C₉H₉N

Purity: 98%

Color and Shape: Solid, Flakes or Granules or Powder

Molecular weight: 131.178

Ref: 10-F003402

2-Methylindole

CAS: 95-20-5

Formula: C₉H₉N

Molecular weight: 131.18

Ref: ST-EA-CP-I21014