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CAS 95056-36-3

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N-7-(2-(Nitrophenyldithio)ethyl)mitomycin C

Description:
N-7-(2-(Nitrophenyldithio)ethyl)mitomycin C is a synthetic derivative of mitomycin C, a well-known antitumor antibiotic. This compound features a nitrophenyldithio group, which enhances its chemical reactivity and potential biological activity. The presence of the nitro group may contribute to its ability to form reactive intermediates, which can interact with cellular macromolecules, including DNA, leading to cytotoxic effects. The dithioether linkage in the structure can also influence its solubility and stability in biological systems. Like other mitomycin derivatives, it is expected to exhibit antineoplastic properties, making it of interest in cancer research. However, its specific pharmacological profile, including mechanisms of action, efficacy, and toxicity, would require further investigation through experimental studies. As with many compounds in this class, safety and handling precautions are essential due to potential mutagenic and carcinogenic properties. Overall, N-7-(2-(Nitrophenyldithio)ethyl)mitomycin C represents a modification aimed at enhancing the therapeutic potential of mitomycin C while also necessitating careful evaluation of its biological effects.
Formula:C23H25N5O7S2
InChI:InChI=1/C23H25N5O7S2/c1-11-17(25-7-8-36-37-13-5-3-12(4-6-13)28(32)33)20(30)16-14(10-35-22(24)31)23(34-2)21-15(26-21)9-27(23)18(16)19(11)29/h3-6,14-15,21,25-26H,7-10H2,1-2H3,(H2,24,31)/t14-,15+,21+,23-/m1/s1
Synonyms:
  • [1aS-(1aalpha,8beta,8aalpha,8balpha)]-8-(Carbamoyloxymethyl)-8a-methoxy-5-methyl-6-[2-(4-nitrophenyldisulfanyl)ethylamino]-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
  • [(1aS,8S,8aR,8bS)-8a-methoxy-5-methyl-6-({2-[(4-nitrophenyl)disulfanyl]ethyl}amino)-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methyl carbamate
  • N-7-(2-(Nitrophenyldithio)ethyl)mitomycin C
  • Azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione, 8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methyl-6-[[2-[(4-nitrophenyl)dithio]ethyl]amino]-, (1aS,8S,8aR,8bS)-
  • PubChem ID: 56855
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Found 3 products.
  • BMS 181174
    TRC
    + Info

    BMS 181174

    Controlled Product
    CAS:
    Formula:C23H25N5O7S2
    Color and Shape:Neat
    Molecular weight:547.604

    Ref: TR-B595910

    25mg
    3,428.00€
  • BMS 181174-d4
    TRC
    + Info

    BMS 181174-d4

    Controlled Product
    CAS:
    Formula:C23D4H21N5O7S2
    Color and Shape:Neat
    Molecular weight:551.629

    Ref: TR-B595912

    25mg
    3,428.00€
  • BMS 181174
    Biosynth
    + Info

    BMS 181174

    CAS:
    <p>Mitomycin C analogue</p>
    Purity:Min. 95%

    Ref: 3D-AN63363

    15mg
    3,477.00€