CAS 951661-85-1

Tadalafil Impurity 21

CAS: 951661-85-1

Formula: C₂₀H₁₉N₃O₃

Color and Shape: White To Off-White Solid

Molecular weight: 349.39

Ref: 4Z-T-108

(1S,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide

Controlled Product

CAS: 951661-85-1

Formula: C₂₀H₁₉N₃O₃

Color and Shape: Neat

Molecular weight: 349.38

Ref: TR-B203535

(1S,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide-d3

Controlled Product

CAS: 951661-85-1

Applications (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide-d3 is the isotope labelled analog of (1S,3R)-1-(1,3-Benzodioxol-5-yl)-2,3,4,9-tetrahydro-N-methyl-1H-pyrido[3,4-b]indole-3-carboxamide (B203535); a byproduct formed in the preparation of Tadalafil (T004500) which is a phosphodiesterase 5 inhibitor used for the treatment of erectile dysfunction.
References Crasto, A.M., et al.: PCT Int. Appl. WO 2007110734 A1 20071004. Oct 4, 2007; Carrier, S., et al.: Can. J. Urol., 10(1), 12 (2003); Doggrell, S.A., et al.: Expert Opin. Pharmacother., 6, 75 (2005); Forgue, S.T., et al.: Br. J. Clin. Pharmacol., 61, 280 (2005)

Formula: C₂₀D₃H₁₆N₃O₃

Color and Shape: Neat

Molecular weight: 352.402

Ref: TR-B203537

Tadalafil Impurity 21

CAS: 951661-85-1

Formula: C₂₀H₁₉N₃O₃

Molecular weight: 349.39

Ref: ST-EA-CP-T31056