CAS 95192-51-1

L-Phenylalanine,N-(3-carboxy-1-oxopropyl)-L-valyl-L-prolylthio-, S-(phenylmethyl) ester (9CI)

Description:

L-Phenylalanine, N-(3-carboxy-1-oxopropyl)-L-valyl-L-prolylthio-, S-(phenylmethyl) ester, with the CAS number 95192-51-1, is a synthetic compound that belongs to the class of amino acid derivatives. This substance features a complex structure that includes multiple amino acid residues, specifically L-phenylalanine, L-valine, and L-proline, linked through peptide bonds. The presence of a thioester functional group indicates that it may participate in various biochemical reactions, potentially serving as a substrate or inhibitor in enzymatic processes. The compound's carboxylic acid and ester functionalities suggest it may exhibit polar characteristics, influencing its solubility in aqueous environments. Additionally, the phenylmethyl group contributes to its hydrophobic properties, which can affect its interactions with biological membranes and proteins. Overall, this compound may have applications in biochemical research, particularly in studies related to peptide synthesis, drug design, or as a potential therapeutic agent, although specific biological activities would require further investigation.

Formula: C₃₀H₃₇N₃O₆S

Synonyms:

• L-Phenylalanine,N-[1-[N-(3-carboxy-1-oxopropyl)-L-valyl]-L-prolyl]thio-, S-(phenylmethyl) ester

Suc-Val-Pro-Phe-SBzl

CAS: 95192-51-1

The thiobenzyl ester substrate Suc-VPF-SBzl is significantly more sensitive than the corresponding p-nitroanilide, with kcat/Km values ranging from 0.5 to 8.3 · 10⁶ M⁻¹s⁻¹ for chymotrypsin, human leukocyte cathepsin G, human skin chymase, and rat mast cell proteases.

Formula: C₃₀H₃₇N₃O₆S

Purity: > 98%

Color and Shape: White Powder

Molecular weight: 567.71

Ref: 01-4018016

Suc-Val-Pro-Phe-SBzl

CAS: 95192-51-1

Suc-Val-Pro-Phe-SBzl is a synthetic subtilisin that has been modified to have an enhanced binding affinity for the enzyme's substrate. The enzyme's specificity and reactivity has been improved by adding a chloromethyl ketone group to the amino acid sequence. Suc-Val-Pro-Phe-SBzl is a serine protease inhibitor and has been shown to inhibit the activity of subtilisins, including subtilisin BPN' and Bacillus amyloliquefaciens subtilisin. It also inhibits peptidases and proteinases, which may be due to its ability to bind to the active site of these enzymes.

Formula: C₃₀H₃₇N₃O₆S

Purity: Min. 95%

Molecular weight: 567.7 g/mol

Ref: 3D-FS110894