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CAS 95197-95-8

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5(6)-TRITC 5(6)-Tetramethylrhodamine isothiocyanate

Description:
5(6)-Tetramethylrhodamine isothiocyanate (TRITC) is a fluorescent dye commonly used in biological and biochemical applications, particularly for labeling proteins, antibodies, and nucleic acids. It is characterized by its bright red fluorescence, which is highly stable and resistant to photobleaching, making it ideal for various imaging techniques, including fluorescence microscopy and flow cytometry. The isothiocyanate functional group allows for covalent bonding to amine groups in proteins, facilitating effective labeling. TRITC has a high molar absorptivity and a relatively large Stokes shift, which enhances its utility in multi-color experiments. Its solubility in organic solvents and aqueous buffers further contributes to its versatility in laboratory settings. However, care must be taken when handling TRITC, as it can be toxic and may cause skin and eye irritation. Overall, TRITC is a valuable tool in the field of molecular biology for visualizing and tracking biomolecules in complex biological systems.
Formula:C25H21N3O3S
InChI:InChI=1/C25H21N3O3S/c1-27(2)16-6-9-19-22(12-16)31-23-13-17(28(3)4)7-10-20(23)24(19)21-11-15(26-14-32)5-8-18(21)25(29)30/h5-13H,1-4H3
SMILES:CN(C)c1ccc2c(c1)[o+]c1cc(ccc1c2c1cc(ccc1C(=O)[O-])N=C=S)N(C)C
Synonyms:
  • 2-[6-(dimethylamino)-3-(dimethyliminio)-3H-xanthen-9-yl]-4-isothiocyanatobenzoate
  • Anti-Human IgG (H+L)-Rhodamine antibody produced in goat
  • Tetramethylrhodamine-5-(and-6)-isothiocyanate, mixed isomers
  • Anti-Mouse IgG F(ab′)2-Rhodamine antibody produced in goat
  • Anti-Human IgG (γ-chain specific)-Rhodamine antibody produced in rabbit
  • Anti-Sheep IgG F(ab′)2-Rhodamine antibody produced in rabbit
  • Anti-Ferret IgG (γ-chain specific)-Rhodamine antibody produced in goat
  • TETRAMETHYLRHODAMINE 5(6)-ISOTHIOCYANATE
  • Anti-Rabbit IgG (H+L)-Rhodamine antibody produced in donkey
  • Anti-Chicken IgG F(ab′)2-Rhodamine antibody produced in rabbit
  • See more synonyms
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