CAS 952-45-4

Cyclo(leucylleucine)

Description:

Cyclo(leucylleucine) is a cyclic dipeptide composed of two leucine amino acids linked together in a ring structure. This compound is characterized by its unique cyclic arrangement, which influences its conformational properties and biological activity. Cyclo(leucylleucine) exhibits hydrophobic characteristics due to the presence of leucine, an aliphatic amino acid, which contributes to its solubility in organic solvents rather than in water. The cyclic nature of this dipeptide can enhance its stability compared to linear peptides, making it of interest in various biochemical applications, including studies on peptide folding and interactions. Additionally, cyclic dipeptides like cyclo(leucylleucine) can exhibit interesting pharmacological properties, potentially acting as inhibitors or modulators in biological systems. Its CAS number, 952-45-4, allows for easy identification and reference in chemical databases. Overall, cyclo(leucylleucine) serves as a valuable compound in both research and potential therapeutic applications due to its structural and functional characteristics.

Formula: C₁₂H₂₂N₂O₂

InChI: InChI=1S/C12H22N2O2/c1-7(2)5-9-11(15)14-10(6-8(3)4)12(16)13-9/h7-10H,5-6H2,1-4H3,(H,13,16)(H,14,15)/t9-,10-/m0/s1

InChI key: InChIKey=XWYXUMDVQIOAPR-UWVGGRQHSA-N

SMILES: C(C(C)C)[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N1

Synonyms:

• 2,5-Piperazinedione, 3,6-bis(2-methylpropyl)-, (3S,6S)-
• (3S,6S)-3,6-Bis(2-methylpropyl)-2,5-piperazinedione
• 2,5-Piperazinedione, 3,6-bis(2-methylpropyl)-, (3S-cis)-
• Cyclo(L-leucyl-L-leucyl)
• 2,5-Piperazinedione, 3,6-diisobutyl-, stereoisomer

(3s,6s)-3,6-bis(2-methylpropyl)piperazine-2,5-dione

CAS: 952-45-4

Formula: C₁₂H₂₂N₂O₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 226.3153

Ref: IN-DA006OIY

Cyclo(Leu-Leu)

CAS: 952-45-4

Formula: C₁₂H₂₂N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 226.32

Ref: 4Z-L-117004

Cyclo(Leu-Leu)

Controlled Product

CAS: 952-45-4

Applications A cyclic peptide, one of the secondary metabolite of a mangrove endophytic fungus (No. 1947) from the South China Sea.
References Carmichael, J., et al.: Cancer Res., 47, 936 (1987), Blunt, J., et al.: Nat. Prod. Rep., 20, 1 (2003), Mitova, M., et al.: J. Nat. Prod., 67, 1178 (2004),

Formula: C₁₂H₂₂N₂O₂

Color and Shape: Neat

Molecular weight: 226.315

Ref: TR-C988300

Cyclo(leu-leu)

CAS: 952-45-4

Cyclo(leu-leu) is a glycosidase inhibitor that has been shown to have an inhibitory effect on the biosynthesis of aminoacylated proteins. Cyclo (leu-leu) is derived from the wild-type strain of a fungus, which is a genus of endophytic fungi. This compound inhibits the synthesis of proteins by binding to glycosylated amino acid residues and preventing their hydrolysis. Cyclo (leu-leu) also has homologous regions with mellein, which is another type of glycosidase inhibitor that binds to the enzyme protein kinase C, inhibiting protein synthesis and leading to cell death.

Formula: C₁₂H₂₂N₂O₂

Purity: Min. 95%

Molecular weight: 226.32 g/mol

Ref: 3D-FC20680