CAS 953778-58-0

MK-8998

CAS: 953778-58-0

Formula: C₂₀H₂₃F₃N₂O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 380.4040

Ref: IN-DA01EB1A

(R)-2-(4-Isopropylphenyl)-N-(1-(5-(2,2,2-Trifluoroethoxy)pyridin-2-yl)Ethyl)AcetaMide

CAS: 953778-58-0

(R)-2-(4-Isopropylphenyl)-N-(1-(5-(2,2,2-Trifluoroethoxy)pyridin-2-yl)Ethyl)AcetaMide

Purity: 98%

Molecular weight: 380.4g/mol

Ref: 54-PC108725

Suvecaltamide

CAS: 953778-58-0

Suvecaltamide

Purity: ≥98%

Molecular weight: 380.4g/mol

Ref: 54-BUP13216

Suvecaltamide

CAS: 953778-58-0

Suvecaltamide (MK-8998) as potent inhibitors of T-type calcium channels.

Formula: C₂₀H₂₃F₃N₂O₂

Purity: 99.29% - 99.70%

Color and Shape: Solid

Molecular weight: 380.4

Ref: TM-T5632

MK-8998

CAS: 953778-58-0

MK-8998 is a drug that blocks the calcium channel and has been investigated as a potential treatment for psychosis. MK-8998 has been found to be effective in reducing symptoms of psychosis in patients with schizophrenia, bipolar disorder, and major depressive disorder. The mechanism of action is thought to be related to its ability to block the calcium channels in the brain, thereby inhibiting neuronal activity. MK-8998 has been shown to have selectivity for the alpha2A subtype of voltage-gated calcium channels (L-, N-, P/Q-, R-, T-) but not the alpha1 or alpha2B subtypes. In vitro studies have demonstrated that MK-8998 inhibits currents through L-, N-, P/Q-, R-, and T-type channels with IC50 values ranging from 0.5 nM to 1 μM.

Formula: C₂₀H₂₃F₃N₂O₂

Purity: Min. 95%

Molecular weight: 380.4 g/mol

Ref: 3D-DNB77858