CAS 953787-54-7

Lansoprazole sulfone N-oxide

Description:

Lansoprazole sulfone N-oxide, identified by its CAS number 953787-54-7, is a chemical compound derived from lansoprazole, a proton pump inhibitor commonly used to treat conditions like gastroesophageal reflux disease (GERD) and peptic ulcers. This compound features a sulfone functional group, which contributes to its chemical stability and solubility properties. As an N-oxide, it contains an oxygen atom bonded to a nitrogen atom, which can influence its reactivity and biological activity. The presence of these functional groups may enhance its pharmacokinetic properties, potentially affecting absorption, distribution, metabolism, and excretion in biological systems. While specific data on its toxicity and environmental impact may be limited, compounds of this nature are typically evaluated for safety in pharmaceutical applications. Overall, lansoprazole sulfone N-oxide represents a modification of the parent drug that may offer insights into the development of new therapeutic agents or formulations.

Formula: C₁₆H₁₄F₃N₃O₄S

InChI: InChI=1/C16H14F3N3O4S/c1-10-13(22(23)7-6-14(10)26-9-16(17,18)19)8-27(24,25)15-20-11-4-2-3-5-12(11)21-15/h2-7H,8-9H2,1H3,(H,20,21)

SMILES: Cc1c(CS(=O)(=O)c2nc3ccccc3[nH]2)n(=O)ccc1OCC(F)(F)F

Synonyms:

• 2-[(RS）-[[3-methyl-1-oxido-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]sulphinyl]-1H-benzimidazole
• 2-[[3-methyl-1-oxido-4-(2,2,2-trifluoroethoxy)pyridin-1-ium-2-yl]methylsulfonyl]-1H-benzimidazole

Lansoprazole EP Impurity B N-Oxide (Lansoprazole USP Related Compound A N-Oxide, Lansoprazole Sulfone N-Oxide)

CAS: 953787-54-7

Formula: C₁₆H₁₄F₃N₃O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 401.36

Ref: 4Z-L-0315

Lansoprazole Sulphone N-Oxide

Controlled Product

CAS: 953787-54-7

Formula: C₁₆H₁₄F₃N₃O₄S

Color and Shape: Neat

Molecular weight: 401.36

Ref: 86-MM0474.08

Lansoprazole Sulfone N-Oxide

CAS: 953787-54-7

Formula: C₁₆H₁₄F₃N₃O₄S

Molecular weight: 401.36

Ref: ST-EA-CP-L11007

Lansoprazole Sulfone N-Oxide

Controlled Product

CAS: 953787-54-7

Applications An impurity of Lansoprazole.
References Barradell, L., et al.: Drugs, 44, 225 (1992), Aydogmus, Z., et al.: Acta Pharm. Sci., 48, 45 (2006), El-Sherif, Z., et al.: Chem. Pharm. Bull., 54, 814 (2006),

Formula: C₁₆H₁₄F₃N₃O₄S

Color and Shape: White

Molecular weight: 401.36

Ref: TR-L175030

Lansoprazole sulfone N-oxide

CAS: 953787-54-7

Lansoprazole sulfone N-oxide is a sulfone that is the active form of lansoprazole. It is used in the treatment of oesophagitis and reflux oesophagitis. Lansoprazole sulfone N-oxide binds to bacterial proteins, which leads to the inhibition of bacterial growth. This drug has been shown to be effective against both duodenal and gastric ulcers. Lansoprazole sulfone N-oxide also inhibits acid secretion by binding to the H+/K+ ATPase pump on parietal cells, thereby inhibiting hydrogen ion secretion into the stomach.

Formula: C₁₆H₁₄F₃N₃O₄S

Purity: Min. 95%

Molecular weight: 401.36 g/mol

Ref: 3D-FL24842