CAS 95440-71-4

Prednisone 17-acetate

Description:

Prednisone 17-acetate is a synthetic corticosteroid with anti-inflammatory and immunosuppressive properties. It is derived from prednisone, a naturally occurring steroid, and features an acetate group at the 17 position, which enhances its pharmacological activity. This compound is typically used in the treatment of various conditions, including autoimmune disorders, allergies, and certain types of cancer. Prednisone 17-acetate exhibits characteristics such as high lipid solubility, allowing for effective cellular penetration and action. Its mechanism of action involves binding to glucocorticoid receptors, leading to the modulation of gene expression and the subsequent reduction of inflammatory mediators. The compound is often administered in various forms, including oral tablets or injectable solutions, depending on the clinical indication. As with other corticosteroids, potential side effects may include immunosuppression, metabolic changes, and hormonal imbalances, necessitating careful monitoring during treatment. Overall, Prednisone 17-acetate is a valuable therapeutic agent in managing inflammatory and autoimmune conditions.

Formula: C₂₃H₂₈O₆

InChI: InChI=1S/C23H28O6/c1-13(25)29-23(19(28)12-24)9-7-17-16-5-4-14-10-15(26)6-8-21(14,2)20(16)18(27)11-22(17,23)3/h6,8,10,16-17,20,24H,4-5,7,9,11-12H2,1-3H3/t16-,17-,20+,21-,22-,23-/m0/s1

InChI key: InChIKey=PCDMOOFTYPHGTF-RFZYENFJSA-N

SMILES: C(CO)(=O)[C@]1(OC(C)=O)[C@]2(C)[C@@](CC1)([C@]3([C@](C(=O)C2)([C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H])[H]

Synonyms:

• Pregna-1,4-diene-3,11,20-trione, 17-(acetyloxy)-21-hydroxy-
• Prednisone 17-acetate
• Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-, 17-acetate
• 17-(Acetyloxy)-21-hydroxypregna-1,4-diene-3,11,20-trione