CAS 95510-70-6

Omeprazole sodium

Description:

Omeprazole sodium is a proton pump inhibitor (PPI) primarily used to treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers by reducing gastric acid secretion. It is a sodium salt form of omeprazole, which is a substituted benzimidazole. The compound is typically characterized by its white to off-white crystalline powder appearance and is soluble in water, making it suitable for oral formulations. Omeprazole sodium works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to decreased acid production. Its pharmacokinetics involve rapid absorption, with peak plasma concentrations occurring within a few hours after administration. The drug is metabolized primarily in the liver and has a relatively short half-life, necessitating once-daily dosing for effective acid suppression. Common side effects may include headache, nausea, and gastrointestinal disturbances. As with other PPIs, long-term use may be associated with certain risks, such as vitamin B12 deficiency and increased susceptibility to gastrointestinal infections.

Formula: C₁₇H₁₉N₃O₃S·Na

InChI: InChI=1S/C17H19N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3,(H,19,20);

InChI key: InChIKey=HVAJOLFRLWQQQL-UHFFFAOYSA-N

SMILES: S(CC1=C(C)C(OC)=C(C)C=N1)(=O)C=2NC=3C(N2)=CC=C(OC)C3.[Na]

Synonyms:

• 1H-Benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt
• 1H-Benzimidazole, 6-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)
• 5-Methoxy-2-(((4-Methoxy-3,5-Dimethyl-2-Pyridinyl)Methyl)Sulfinyl)-1H-Benzimidazole Sodium Salt
• 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole sodium salt
• 5-Methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl]-1H-benzimidazole sodium salt
• H 168/68 sodium
• Losec Sodium
• Omeprazole Sodium
• Omeprazole powder/pellets/sodium
• Omeprazole, sodium salt
• Sodium omeprazole

5-​Methoxy-​2-​[[(4-​methoxy-​3,​5-​dimethyl-​2-​pyridyl)​methyl]​sulfinyl]​-​1H-​benzimidazole sodium salt

CAS: 95510-70-6

Formula: C₁₇H₁₉N₃NaO₃S

Purity: %

Color and Shape: Solid

Molecular weight: 368.4058

Ref: IN-DA00IJ66

Omeprazole Sodium

CAS: 95510-70-6

Omeprazole Sodium

Purity: ≥98%

Molecular weight: 367.4g/mol

Ref: 54-BUP16867

Omeprazole sodium salt

CAS: 95510-70-6

Formula: C₁₇H₁₉N₃NaO₃S

Purity: ≥ 98.0%

Color and Shape: White powder

Molecular weight: 368.41

Ref: 7W-GP2367

Omeprazole Sodium

CAS: 95510-70-6

Color and Shape: Neat

Ref: 61-FOR3011.00

Omeprazole Sodium

CAS: 95510-70-6

Formula: C₁₇H₁₈N₃O₃S·Na·H₂O

Color and Shape: Neat

Molecular weight: 385.41

Ref: 86-MM3011.00

Omeprazole Sodium Salt

Controlled Product

CAS: 95510-70-6

Stability Hygroscopic
Applications Omeprazole Sodium Salt is the salt analogue of Omeprazole (O635000), which binds covalently to proton pump. It inhibits gastric secretion. Used as an anttiulcerative.
References Muller, P., et al.: Arzneimittel-Forsch., 33, 1685 (1983); Wallmark, B., et al.: Biochim. Biophys. Acta., 778, 549 (1984); Morii, M., et al.: J. Biol. chem., 268, 21553 (1993); Ritter, M., et al.: Br. J. Pharmacol., 124, 627 (1998)

Formula: C₁₇H₁₈N₃O₃S·Na·H₂O

Color and Shape: Off-White

Molecular weight: 385.41

Ref: TR-O635013

Omeprazole sodium salt hydrate

CAS: 95510-70-6

Proton pump inhibitor; irreversible blocker of P-type H+/K+ ATPase

Formula: C₁₇H₁₈N₃O₃S•Na•xH₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 367.41 g/mol

Ref: 3D-FO67914

Omeprazole sodium salt monohydrate - Bio-X ™

CAS: 95510-70-6

Omeprazole is a proton pump inhibitor (PPI) that inhibits the production of gastric acid in the stomach. This is due to Omeprazole binding through a stable disulphide bond to the H+/K+ ATPase enzyme found on parietal cells, and preventing hydrogen ion transport. Consequently, gastric acid secretion is supressed. As a PPI, Omerprazole can be used to treat disorders where gastric acid is over-secreted. Examples of these disorders are gastroesophageal reflux disease (GERD) and peptic ulcer disease.

Formula: C₁₇H₁₈N₃O₃S·Na·H₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 386.41 g/mol

Ref: 3D-BO164175

Omeprazole Sodium

CAS: 95510-70-6

Omeprazole Sodium is a proton pump inhibitor(PPI) and suppresses gastric acid secretion.

Formula: C₁₇H₁₈N₃NaO₃S

Purity: 99.84%

Color and Shape: Clear In Water

Molecular weight: 367.4

Ref: TM-T22391