CAS 95522-45-5

Colestilan

Description:

Colestilan, with the CAS number 95522-45-5, is a synthetic polymeric compound primarily used as a cholesterol-lowering agent. It functions by binding bile acids in the gastrointestinal tract, which promotes the excretion of cholesterol and helps reduce overall cholesterol levels in the body. Colestilan is classified as a bile acid sequestrant and is often utilized in the management of hyperlipidemia, particularly in patients who are intolerant to statins or require additional lipid-lowering therapy. The substance is typically administered orally and is known for its ability to improve lipid profiles without significantly affecting the absorption of other nutrients. Its safety profile is generally favorable, although potential side effects may include gastrointestinal disturbances such as constipation or diarrhea. As a polymer, Colestilan's structure allows for effective binding to bile acids, enhancing its therapeutic efficacy. Overall, Colestilan represents a valuable option in the pharmacological management of cholesterol-related conditions.

Formula: C₆H₉N₂OX₂·Cl

InChI: InChI=1/C4H6N2.C3H5ClO/c1-4-5-2-3-6-4;4-1-3-2-5-3/h2-3H,1H3,(H,5,6);3H,1-2H2

InChI key: InChIKey=DEMLYXMVPJAVFU-UHFFFAOYSA-N

SMILES: CC=1NC=CN1.C(Cl)C1CO1

Synonyms:

• 1H-Imidazole, 2-methyl-, polymer with (chloromethyl)oxirane
• 1H-Imidazole, 2-methyl-, polymer with 2-(chloromethyl)oxirane
• 2-(chloromethyl)oxirane - 2-methyl-1H-imidazole (1:1)
• 2-Methylimidazole polymer with 1-chloro-2,3-epoxypropane
• BindRen
• Cholebine
• Colestilan chloride
• Colestimide
• Epichlorohydrin-2-methylimidazole copolymer
• Mci 196
• Oxirane, (chloromethyl)-, polymer with 2-methyl-1H-imidazole
• 2-(chloromethyl)oxirane,2-methyl-1H-imidazole

Colestilan

CAS: 95522-45-5

Colestilan (MCI-196), a non-absorbable, non-calcium-based phosphate binder and anion exchange resin, exhibits oral activity and is utilized in the study of

Color and Shape: Solid

Ref: TM-T82695

Colestilan

Controlled Product

CAS: 95522-45-5

Applications Colestilan, is a copolymer of 2-methyl-1H-imidazole and epichlorohydrin, and a bile acid sequestrans, that can be used for the treatment of hypercholesterolemia and dyslipidemia.
References Handelsman, Y., et al.: Diabetes Care, 34, S244 (2011);

Formula: C₄H₆N₂·C₃H₅ClO

Color and Shape: Neat

Molecular weight: 174.63

Ref: TR-C640090

Colestilan

CAS: 95522-45-5

Please enquire for more information about Colestilan including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₇H₁₁ClN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 174.63 g/mol

Ref: 3D-VDA52245