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CAS 955288-52-5

:

4-chloro-8-(trifluoromethyl)quinolin-2(1H)-one

Description:
4-Chloro-8-(trifluoromethyl)quinolin-2(1H)-one is a synthetic organic compound belonging to the quinoline family, characterized by a fused bicyclic structure that includes a nitrogen atom in its aromatic ring. This compound features a chloro substituent at the 4-position and a trifluoromethyl group at the 8-position, which significantly influences its chemical properties and reactivity. The presence of the trifluoromethyl group enhances lipophilicity and can affect the compound's biological activity, making it of interest in medicinal chemistry. The quinolinone moiety contributes to its potential as a pharmacophore, with applications in drug development, particularly in the fields of antimicrobial and anticancer research. The compound is typically solid at room temperature and may exhibit moderate solubility in organic solvents. Its reactivity can be attributed to the electron-withdrawing nature of the chloro and trifluoromethyl groups, which can influence nucleophilic attack and other chemical interactions. Safety data should be consulted for handling, as halogenated compounds can pose environmental and health risks.
Formula:C10H5ClF3NO
InChI:InChI=1/C10H5ClF3NO/c11-7-4-8(16)15-9-5(7)2-1-3-6(9)10(12,13)14/h1-4H,(H,15,16)
SMILES:c1cc2c(cc(nc2c(c1)C(F)(F)F)O)Cl
Synonyms:
  • 2(1H)-quinolinone, 4-chloro-8-(trifluoromethyl)-
  • 4-Chloro-8-(trifluoromethyl)quinolin-2(1H)-one
  • 4-Chloro-1,2-dihydro-2-oxo-8-(trifluoromethyl)quinoline
  • 4-CHLORO-8-TRIFLUOROMETHYL-1H-QUINOLIN-2-ONE
  • 4-CHLORO-2-HYDROXY-8-TRIFLUOROMETHYLQUINOLINE
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