CAS 95549-92-1

(±)-1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-methoxypropionyl)piperazine

Description:

(±)-1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-methoxypropionyl)piperazine, with CAS number 95549-92-1, is a chemical compound that belongs to the class of piperazine derivatives. This substance features a piperazine ring, which is a six-membered heterocyclic compound containing two nitrogen atoms. The presence of a quinazoline moiety, specifically a 4-amino-6,7-dimethoxy-2-quinazoline structure, contributes to its potential biological activity. The methoxypropionyl group enhances its lipophilicity, which may influence its pharmacokinetic properties. This compound is of interest in medicinal chemistry due to its potential therapeutic applications, possibly in the treatment of various conditions, although specific biological activities would require further investigation. Its stereochemistry is indicated by the (±) notation, suggesting that it exists as a racemic mixture of enantiomers. As with many synthetic compounds, safety and handling precautions should be observed, and its stability, solubility, and reactivity would depend on the specific conditions under which it is used.

Formula: C₁₈H₂₅N₅O₄

InChI: InChI=1S/C18H25N5O4/c1-11(25-2)17(24)22-5-7-23(8-6-22)18-20-13-10-15(27-4)14(26-3)9-12(13)16(19)21-18/h9-11H,5-8H2,1-4H3,(H2,19,20,21)

InChI key: InChIKey=YEOTYALSMRNXLJ-UHFFFAOYSA-N

SMILES: NC=1C2=C(N=C(N1)N3CCN(C(C(OC)C)=O)CC3)C=C(OC)C(OC)=C2

Synonyms:

• (±)-4-Amino-6,7-dimethoxy-2-[4-(2-methoxypropionyl)piperazino]quinazoline
• 1-Propanone, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-methoxy-
• 1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-methoxy-1-propanone
• Kenosin
• Metazosin
• Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-methoxy-1-oxopropyl)-
• Vufb-15111
• (+-)-4-Amino-2-(4-(2-methoxypropionyl)piperazino)-6,7-dimethoxyquinazoline
• 1-[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-2-methoxypropan-1-one
• Vufb15111
• 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-methoxy-1-oxopropyl)piperazine

Metazosin

Controlled Product

CAS: 95549-92-1

Applications Metazosin is an α-adrenergic receptor antagonist useful in the treatment of hypertension and cardiac insufficiency. It is also used in the preparation of injectable solutions containing quinazolinyl propionyl piperazine.
References Konig, J., et al.: From Czech Rep. (1997), CZ 282948 B6 19971112, Stehlik, P., et al.: J. Chromatogr. Biomed. Appl. 529, 245 (1990)

Formula: C₁₈H₂₅N₅O₄

Color and Shape: Neat

Molecular weight: 375.422

Ref: TR-M216960

Metazosin

CAS: 95549-92-1

Metazosin is an antihypertensive agent that replaces 3H-prazosin from its bond to alpha-1 receptors of the cerebral cortex.

Formula: C₁₈H₂₅N₅O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 375.42

Ref: TM-T25793