CAS 956274-94-5

α,α-Dimethyl-2-[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1H-benzimidazol-6-yl]benzenemethanol

Description:

α,α-Dimethyl-2-[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1H-benzimidazol-6-yl]benzenemethanol, with CAS number 956274-94-5, is a complex organic compound characterized by its multi-functional structure. It features a benzimidazole moiety, which is known for its biological activity, particularly in pharmaceuticals. The presence of a trifluoromethyl group enhances its lipophilicity and may influence its interaction with biological targets. The compound also contains multiple aromatic rings, contributing to its stability and potential for π-π stacking interactions. Its hydroxyl group (alcohol functional group) suggests it may exhibit hydrogen bonding capabilities, which can affect its solubility and reactivity. This compound is likely to be of interest in medicinal chemistry due to its structural features that may confer specific biological activities, although detailed studies would be necessary to elucidate its properties and potential applications fully. As with many complex organic compounds, its synthesis and handling require careful consideration of safety and environmental factors.

Formula: C₂₅H₂₁F₃N₂O

InChI: InChI=1S/C25H21F3N2O/c1-24(2,31)20-6-4-3-5-19(20)17-10-13-21-22(15-17)30-23(29-21)14-9-16-7-11-18(12-8-16)25(26,27)28/h3-15,31H,1-2H3,(H,29,30)/b14-9+

InChI key: InChIKey=ORDHXXHTBUZRCN-NTEUORMPSA-N

SMILES: C(=C/C1=CC=C(C(F)(F)F)C=C1)\C=2NC=3C(N2)=CC=C(C3)C4=C(C(C)(C)O)C=CC=C4

Synonyms:

• Benzenemethanol, α,α-dimethyl-2-[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1H-benzimidazol-6-yl]-
• α,α-Dimethyl-2-[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1H-benzimidazol-6-yl]benzenemethanol
• JNJ 39439335
• Mavatrep
• CS-1660
• Mavatrep(JNJ-39439335)
• (trans)-2-(2-{2-[2-(4-trifluoromethylphenyl)vinyl]-1H-benzimidazol-5-yl}phenyl)propan-2-ol
• JNJ 39439335;JNJ39439335

Mavatrep

CAS: 956274-94-5

Mavatrep

Purity: ≥98%

Molecular weight: 422.44g/mol

Ref: 54-BUP09611

Mavatrep

CAS: 956274-94-5

TRPV1 antagonist

Formula: C₂₅H₂₁F₃N₂O

Purity: Min. 95%

Molecular weight: 422.1606

Ref: 3D-FM145131

Mavatrep

CAS: 956274-94-5

Mavatrep (JNJ-39439335) is a selective antagonist of TRPV1 with Ki of 6.5 nM and can be used for studies about inflammatory pain.

Formula: C₂₅H₂₁F₃N₂O

Purity: 98.51% - 99.31%

Color and Shape: Solid

Molecular weight: 422.44

Ref: TM-T16014